磁调控微/纳米机器人的理化性质及其医学应用现状和进展

Physicochemical properties of magnetically controlled micro/nano robot and its current situation and prospects

体内靶向递送一直是临床医学迫切希望攻克的难题。磁调控微/纳米机器人具有远程控制移动、无束缚接触、精确的靶向能力和对生物物质不敏感等优点而受到研究者的青睐。其应用范围涉及靶向给药、精准手术、细胞操作、疾病诊疗等,在多种生物医学应用方面具有巨大的潜力。近年来关于磁调控微/纳米机器人的研究取得了一定进展。本文就磁调控微/纳米机器人的磁性和可操作性、生物医学、可视化追踪及生物安全性4个方面的研究和应用进展进行综述。

Targeted delivery in vivo has always been a difficulty that clinical medicine is eager to overcome. Magnetically controlled micro/nano robots are favored by researchers because of their advantages,such as remote control of movement,unbound contact,accurate targeting ability and insensitivity to biological substances. Its application range involves targeted drug delivery,precision surgery,cell operation,disease diagnosis and treatment,etc.,which has great potential in a variety of biomedical applications. In recent years,some progress has been made in the research of magnetically controlled micro/nano robots. This review focuses on the magnetism,maneuverability,biomedical application,visual tracking and biosafety of magnetically controlled micro/nano robots.