Effect of sugammadex on the recovery profiles of cardiac patients undergoing non-cardiac surgery

To the Editor:The global trend of an aging population and an epidemic of coronary heart diseases(CHDs)have led to an increasing volume of non-cardiac surgeries in patients with CHDs.[1,2]Drastic fluctuation of hemodynamic parameters can be life-threatening for CHD patients with little tolerance to the increased cardiac load and decreased oxygen delivery.[3]Residual paralysis of muscle relaxation after general anesthesia may lead to hypoxemia with respiratory muscle weakness and aggravate the patient's tension.The cholinesterase inhibitor neostigmine is routinely used to reverse the neuromuscular blockade(NMB)after surgeries under general anesthesia.However,the combined use of neostigmine and atropine in patients with CHD may be potentially problematic because of side effects,such as myocardial ischemia,cardiac arrhythmia,or atrioventricular block.[4]Sugammadex is a new NMB reversal that is selective for steroidal muscle relaxants,particularly rocuronium.However,the effect of sugammadex on the recovery profiles of CHD patients has not been fully elucidated.