注射用丹参多酚酸盐治疗急性脑梗死的临床疗效分析

Analysis of Clinical Efficacy of Salvia Miltiorrhiza Polyphenolate for Injection in Treating Acute Cerebral Infarction

目的分析注射用丹参多酚酸盐在急性脑梗死患者临床治疗中的应用效果。方法该次研究中的研究对象均方便抽选于2020年7月—2021年5月时间段在该院接受诊治的急性脑梗死患者,例数为80例,基于抽签方式将患者划分为两组,两组患者均接受阿司匹林、阿托伐他汀等常规药物治疗,在其基础上对照组借助注射用血塞通进行治疗,研究组借助注射用丹参多酚酸盐进行治疗,对两组患者临床治疗效果予以比较。结果研究组患者MoCA评分、Barthel指数、NIHSS评分和C反应蛋白指标分别为(23.73±2.36)分、(83.25±2.42)分、(2.34±0.89)分、(2.05±0.68)mg/L,其数据均显著优于对照组,差异有统计学意义(t=7.339、18.018、8.033、6.368,P<0.001);研究组患者临床治疗总有效率为92.5%,显著高于对照组,差异有统计学意义(χ^(2)=5.541,P=0.018)。结论应用注射用丹参多酚酸盐对患者施以药物治疗,可有效缓解患者神经功能损伤,提升患者认知功能,并可改善患者临床指标和生活质量,值得在临床上广泛推荐。

Objective To analyze the application effect of Salvia miltiorrhiza polyphenolate for injection in the clinical treatment of patients with acute cerebral infarction.Methods The research object in this study were convenience selected from July 2020 to May 2021 in patients with acute cerebral infarction who were diagnosed and treated in the hospital.The number of patients was 80.The patients were divided into two groups based on the lottery method.Both groups of patients received conventional drug treatments such as aspirin and atorvastatin.On the basis of this,the control group was treated with Xuesaitong for injection,and the study group was treated with injection of Salvia miltiorrhiza polyphenolate.The two groups of patients were compared of the effects.Results The MoCA score,Barthel index,NIHSS score and C-reactive protein index of the study group were(23.73±2.36)points,(83.25±2.42)points,(2.34±0.89)points,(2.05±0.68)mg/L,respectively.The data were significantly better than those of the control group,the difference was statistically significant(t=7.339,18.018,8.033,6.368,P<0.001);the total effective rate of clinical treatment in the study group was 92.5%,which was significantly higher than the control group,the difference was statistically significant(χ^(2)=5.541,P=0.018).Conclusion The application of Salvia miltiorrhiza polyphenolate for injection to the patients can effectively alleviate the neurological damage of the patients,enhance the cognitive function of the patients,and improve the clinical indicators and quality of life of the patients.It is worthy of clinical recommendation.