婴儿期各月龄间超重或肥胖的相关性研究

The correlation study on overweight or obesity of different months in infancy

目的探讨婴儿期各月龄的超重或肥胖与后续月龄超重或肥胖之间的相关性,为儿童超重或肥胖的早期干预策略提供依据。方法选择2019年10月至2020年2月在安徽省妇幼保健院儿童保健科进行健康体检的12月龄儿童,回顾性收集其出生、42 d、3月龄、6月龄和12月龄的体格生长发育记录。分析各月龄超重或肥胖的情况及与后续各月龄超重或肥胖的相关性。结果共收集378例12月龄儿童,出生巨大儿22例(5.8%),42 d、3月龄、6月龄和12月龄超重或肥胖分别为10例(2.6%)、17例(4.5%)、27例(7.1%)、23例(6.1%)。单因素分析显示,出生巨大儿,6月龄和12月龄超重或肥胖更多;42 d超重或肥胖,3月龄超重或肥胖更多;3月龄超重或肥胖,6月龄和12月龄超重或肥胖更多;6月龄超重或肥胖,12月龄超重或肥胖更多;差异均有统计学意义(P<0.05)。多因素分析显示,出生巨大儿,12月龄超重或肥胖更多(OR=5.386);42 d超重或肥胖,3月龄超重或肥胖更多(OR=5.782);3月龄超重或肥胖,6月龄和12月龄超重或肥胖更多(OR=11.957,7.886);6月龄超重或肥胖,12月龄超重或肥胖更多(OR=11.893);差异均有统计学意义(P<0.05)。结论婴儿期是肥胖控制的一个关键时期,各月龄超重或肥胖是儿童后续超重或肥胖的危险因素。

Objective To explore the correlation between overweight or obesity at different months of infancy and that in subsequent months;to provide evidence for the early intervention of overweight or obesity in children.Methods The physical records at birth,42 days,3 months,6 months and 12 months were retrospectively collected from 12-month-old children who underwent physical examination in the Child Healthcare Clinic of Anhui Maternal and Child Healthcare Hospital from October 2019 to February 2020.The situation of overweight or obesity in each month age and its correlation with overweight or obesity in subsequent month ages was analyzed.Results Among the 37812-month infants surveyed,22(5.8%)infants were macrosomia at birth,10(2.6%),17(4.5%),27(7.1%),and 23(6.1%)infants were overweight or obese at 42 days,3 months,6 months,and 12 months,respectively.The univariate analysis showed that macrosomia were more likely to be overweight or obese at 6 months and 12 months.Those who were overweight or obese at 42 days were more likely to be overweight or obese at 3 months.The infants with overweight or obese at 3 months,were more likely to be overweight or obese at 6 months and 12 months.Those with overweight or obese at 6 months,were more likely to be overweight or obese at 12 months.The differences were all statistically significant(P<0.05).Multivariate analysis showed that macrosomia was more likely to be overweight or obese at 12 months(OR=5.386).Those who were overweight or obese at 42 days were more likely to be overweight or obese at 3 months(OR=5.782).Being overweight or obese at 3 months,were more likely to be overweight or obese at 6 months and 12 months(OR=11.957,OR=7.886).Being overweight or obese at 6 months,were more likely to be overweight or obese at 12 months(OR=11.893).The differences were all statistically significant(P<0.05).Conclusion Infancy is a crucial period for obesity control.Overweight or obesity in every month of age is a risk factor for overweight or obesity at subsequent months.