肠三针治疗脓毒症肠功能障碍的临床疗效观察

Clinical efficacy of electroacupuncture at"Intestine Three Needles"in the treatment of intestinal dysfunction in sepsis

目的:探讨电针肠三针对脓毒症肠功能障碍的改善效果。方法:将60例脓毒症肠功能障碍病人,随机分为观察组和对照组,各30例,观察治疗前及治疗后7 d的临床疗效、血清炎症指标、血浆胃动素水平、胃肠功能指标、APACHE-Ⅱ评分、胃肠功能AGI评分情况。结果:2组病人治疗前各指标差异均无统计学意义(P>0.05),治疗后血清炎症指标、排便测量分、腹围、腹内压、APACHE-Ⅱ评分、胃肠功能AGI评分均下降,血浆胃动素水平、每分钟肠鸣音次数均升高,且观察组均优于对照组,差异均有统计学意义(P<0.05~P<0.01);治疗7 d后观察组总有效率优于对照组(P<0.05)。结论:电针肠三针能显著增强脓毒症病人胃肠动力,减弱胃肠道炎症反应,改善胃肠道功能。

Objective:To observe the clinical efficacy of electroacupuncture at"Intestine Three Needles"in the treatment of intestinal dysfunction in sepsis.Methods:A total of 60 sepsis patients with intestinal dysfunction were randomly divided into the control group and observation group(30 cases in each group).The clinical efficacy,serum inflammatory markers,plasma motilin level,gastrointestinal function index,APACHE-Ⅱscore and gastrointestinal function AGI score in two groups were observed before and after 7 days of treatment.Results:There was no statistical significance in each index between two groups before treatment(P>0.05).After treatment,the serum inflammation index,measuring points of defecating,intra-abdominal pressure,abdomen circumference,APACHE-Ⅱscore and gastrointestinal AGI score decreased,the motilin level and number of bowel sounds per minute increased,and the above indexes in observation group were better than those in control group(P<0.05 to P<0.01).The total effective rate in observation group was better than that in control group after 7 days of treatment(P<0.05).Conclusions:Electroacupuncture at“Intestine Three Needles”can significantly enhance the gastrointestinal motility,reduce the gastrointestinal inflammation and improve the gastrointestinal function.