胺碘酮治疗急性心肌梗死后室性心律失常的临床效果分析

Clinical effect analysis of amiodarone on ventricular arrhythmia after acute myocardial infarction

目的探讨胺碘酮治疗急性心肌梗死后室性心律失常的临床效果。方法120例急性心肌梗死后室性心律失常患者,根据治疗模式的差异分为对照组以及观察组,各60例。对照组实施利多卡因治疗,观察组采取胺碘酮治疗。比较两组治疗前后相关指标、治疗效果、心电图恢复正常ST段表现的时间、住院时间。结果治疗后,观察组左室射血分数高于对照组,美国纽约心脏病学会(NYHA)分级、左心室收缩和舒张末期内径、心室率低于对照组,差异有统计学意义(P<0.05)。观察组治疗总有效率68.33%高于对照组的50.00%,差异有统计学意义(P<0.05)。观察组心电图恢复正常ST段表现的时间(6.23±1.45)d、住院时间(8.52±1.26)d均短于对照组的(8.24±1.26)、(12.45±2.21)d,差异有统计学意义(P<0.05)。结论急性心肌梗死后室性心律失常患者采用胺碘酮治疗可更好改善患者的心功能,缩短住院的时间,值得推广。

Objective To discuss the clinical effect of amiodarone on ventricular arrhythmia after acute myocardial infarction.Methods A total of 120 patients with ventricular arrhythmia after acute myocardial infarction were divided into control group and observation group according to the difference of treatment mode.The control group was treated with lidocaine,and the observation group was treated with amiodarone.Both groups were compared in terms of related indicators before and after treatment,therapeutic effect,time for electrocardiogram recovery of normal ST-segment performance,hospitalization time.Results After treatment,the left ventricular ejection fraction in the observation group was higher than that in the control group,and the New York Heart Association(NYHA)classification,left ventricular systolic and left ventricular end-systolic diameter,left ventricular end-diastolic diameter and ventricular rate in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The total effective rate of treatment 68.33%in the observation group was higher than 50.00%in the control group,and the differences were statistically significant(P<0.05).The time for electrocardiogram recovery of normal ST-segment performance(6.23±1.45)d and hospitalization time(8.52±1.26)d in the observation group were shorter than(8.24±1.26)and(12.45±2.21)d in the control group,and the difference was statistically significant(P<0.05).Conclusion Amiodarone can better improve the cardiac function of patients with ventricular arrhythmia after acute myocardial infarction,and shorten their hospitalization time,and it is worthy of promotion.