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纤支镜肺泡灌洗对重症肺炎患者炎性指标及血清sTREM-1和HMGB1水平的影响 被引量:2

The effect of bronchoscopic alveolar lavage on inflammatory indexes and serum sTREM-1 and HMGB1 levels in patients with severe pneumonia
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摘要 目的探讨纤支镜肺泡灌洗对重症肺炎患者炎性指标及血清可溶性髓系细胞触发受体-1(sTREM-1)与高迁移率族蛋白B1(HMGB1)水平的影响。方法选取2017年8月至2020年5月于本院就诊的67例重症肺炎患者,按随机数表方法分为对照组(n=33)和观察组(n=34)。对照组予以常规治疗,观察组在对照组基础上予以纤支镜肺泡灌洗治疗,治疗2周后,比较两组临床疗效、炎性指标[血清降钙素原(PCT)、C反应蛋白(CRP)、白细胞(WBC)]及血清sTREM-1、HMGB1水平。结果观察组治疗总有效率为91.18%,高于对照组的72.73%(P<0.05);治疗后,两组PCT、CRP、sTREM-1、HMGB1、WBC均低于治疗前,且观察组低于对照组(P<0.05)。结论纤支镜肺泡灌洗治疗重症肺炎患者,可有效控制患者炎症反应,显著提高临床疗效。
作者 李丽 LI Li
出处 《当代医学》 2021年第31期168-169,共2页 Contemporary Medicine
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