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特发性矮小症患儿血清IGF-1的水平与其体质量指数的相关性

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摘要 目的:探讨特发性矮小症(ISS)患儿血清胰岛素样生长因子-1(IGF-1)的水平与其体质量指数(BMI)的相关性。方法:选取2020年4月至2022年3月于广州市花都区妇幼保健院就诊的80例ISS患儿作为研究对象。将这80例患儿作为研究组,另选取同期于该院门诊接受健康检查的80例健康儿童作为对照组。检测两组儿童血清生长激素(GH)、IGF-1的水平和BMI,并采用Spearman秩相关性分析法分析研究组患儿血清IGF-1的水平与其BMI的相关性。结果:研究组患儿血清GH、IGF-1的水平、身高、体重、BMI均低于对照组儿童,差异有统计学意义(P<0.05)。进行Spearman秩相关分析的结果显示,研究组患儿血清GH、IGF-1的水平与其身高、BMI均呈正相关。结论:与同龄健康儿童相比,ISS患儿血清IGF-1、GH的水平明显偏低,其血清GH、IGF-1的水平与其身高、BMI均呈正相关。
作者 梁小红 谭迪
出处 《当代医药论丛》 2021年第21期35-36,共2页
基金 广州市花都区科技计划项目(20-HDWS-060),项目名称:特发性矮小症患儿IGF-1与体质量指数的相关研究。
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