芪蛭三七汤治疗冠心病稳定型心绞痛气虚血瘀证的疗效

Effect of Qizhi Sanqi Decoction on the treatment of stable angina pectoris due to coronary heart disease with Qi-deficiency and blood-stasis syndrome

目的分析芪蛭三七汤治疗冠心病稳定型心绞痛气虚血瘀证的疗效。方法60例冠心病稳定型心绞痛气虚血瘀证患者,采用随机数字表法分为观察组和对照组,每组30例。对照组接受常规方法治疗,观察组在对照组基础上加服芪蛭三七汤治疗。比较两组患者的临床疗效、治疗前后血液流变学指标及中医证候积分。结果观察组治疗总有效率93.33%(28/30)高于对照组的73.33%(22/30),差异有统计学意义(P<0.05)。治疗后,观察组胸痛、胸闷、心悸、乏力、气短等中医证候积分、红细胞聚集指数、全血比粘度、血浆比粘度分别为(0.43±0.11)分、(0.42±0.10)分、(0.47±0.13)分、(0.35±0.12)分、(0.30±0.10)分、(9.54±0.21)、(4.12±0.20)mPa·s、(1.62±0.21)mPa·s,均低于对照组的(1.36±0.15)分、(1.23±0.12)分、(1.42±0.13)分、(0.98±0.23)分、(1.25±0.12)分、(10.12±0.42)、(5.43±0.24)mPa·s、(1.82±0.12)mPa·s,差异有统计学意义(P<0.05)。结论芪蛭三七汤治疗冠心病稳定型心绞痛气虚血瘀证的疗效确切,可有效改善血液流变学和患者症状,治疗安全性高,值得推广。

Objective To analyze the efficacy of Qizhi Sanqi Decoction on the treatment of stable angina pectoris due to coronary heart disease with Qi-deficiency and blood-stasis syndrome.Methods A total of 60 patients with stable angina pectoris due to coronary heart disease with Qi-deficiency and blood-stasis syndrome were divided into observation group and control group according to random numerical table,with 30 cases in each group.The control group received conventional treatment,and the observation group was treated with Qizhi Sanqi Decoction on the basis of the control group.The clinical efficacy,hemorheology indexes before and after treatment,and traditional Chinese medicine syndrome scores were compared between the two groups.Results The total effective rate of treatment 93.33%(28/30)in the observation group was higher than 73.33%(22/30)in the control group,and the difference was statistically significant(P<0.05).After treatment,the traditional Chinese medicine syndrome scores of chest pain,chest tightness,palpitation,weakness and shortness of breath,erythrocyte aggregation index,whole blood specific viscosity and plasma specific viscosity in the observation group were(0.43±0.11)points,(0.42±0.10)points,(0.47±0.13)points,(0.35±0.12)points,(0.30±0.10)points,(9.54±0.21),(4.12±0.20)mPa·s,(1.62±0.21)mPa·s,which were lower than(1.36±0.15)points,(1.23±0.12)points,(1.42±0.13)points,(0.98±0.23)points,(1.25±0.12)points,(10.12±0.42),(5.43±0.24)mPa·s,(1.82±0.12)mPa·s in the control group,and the differences were statistically significant(P<0.05).Conclusion Qizhi Sanqi Decoction has definite efficacy on the treatment of stable angina pectoris due to coronary heart disease with Qi-deficiency and blood-stasis syndrome,and it can effectively improve hemorheology and symptoms of patients with high safety,which is worthy of promotion.