药学干预预防使用抗菌药物在骨科Ⅰ类切口围术期的效果观察

Observation of the effect of pharmaceutical intervention with antibacterial drugs on perioperative patients with orthopedic classⅠincision

目的观察药学干预预防使用抗菌药物在骨科Ⅰ类切口患者围术期的效果。方法40例骨科进行Ⅰ类切口手术的患者,使用随机数字表法分为实验组和对照组,每组20例。两组均预防使用抗菌药物,对照组患者未进行药学干预,实验组患者进行药学干预。比较两组患者术后感染率、抗菌药物给药时机合理性。结果实验组术后感染率5%显著低于对照组的35%,差异具有统计学意义(P<0.05)。实验组抗菌药物给药时机合理率90%显著高于对照组的55%,差异具有统计学意义(P<0.05)。结论对骨科Ⅰ类切口围术期患者实施药学干预预防使用抗菌药物,可以提高抗菌药物使用合理性,降低患者感染的发生几率。

Objective To observe the effect of pharmaceutical intervention with antibacterial drugs on perioperative patients with orthopedic classⅠincision.Methods A total of 40 orthopedic patients undergoing classⅠincision surgery were divided into experimental group and control group according to random numerical table,with 20 cases in each group.Antibacterial drugs were used preventively in both groups.Patients in the control group did not implement pharmaceutical intervention,and patients in the experimental group implemented pharmaceutical intervention.The postoperative infection rate and rationality of antimicrobial drug administration were compared between two groups.Results The postoperative infection rate 5%in the experimental group was significantly lower than 35%in the control group,and the difference was statistically significant(P<0.05).The rationality of antimicrobial administration 90%in the experimental group was significantly higher than 55%in the control group,and the difference was statistically significant(P<0.05).Conclusion Pharmaceutical intervention with antibacterial drugs for perioperative patients with orthopedic classⅠincision can improve the rationality of antibacterial drugs and reduce the risk of infection.