阴茎部分切除加延长术治疗早期阴茎癌的临床效果

Clinical effect of partial penectomy and penile lengthening in the treatment of early penile cancer

目的 探讨阴茎部分切除加延长术治疗早期阴茎癌的临床效果。方法 选取我院2018年1月至2020年1月收治的早期阴茎癌患者50例,以随机数字表法分为两组,对照组25例采用阴茎全切术,研究组25例采用阴茎部分切除加延长术。对比两组患者手术时长、术中出血量、术后疼痛评分、术后肿瘤复发、切口感染、尿道外口狭窄、排尿情况,术前及术后SAS评分、SDS评分。结果 研究组手术时间长于对照组,术中出血量高于对照组,术后疼痛评分低于对照组,差异有统计学意义(P<0.05);两组患者术后皆无肿瘤复发、切口感染、尿道外口狭窄情况发生;对照组术后配合尿道会阴造瘘,患者蹲式排尿正常,研究组术后皆正常站立排尿,排尿功能无影响;两组患者术前SAS评分、SDS评分显著差异无统计学意义(P>0.05),术后研究组SAS评分(48.3±4.5)分、SDS评分(52.2±4.0)分,低于对照组的(64.2±5.8)分、(63.3±4.8)分,差异有统计学意义(t=10.830,8.883,P<0.05)。结论 早期阴茎癌临床治疗中,采用阴茎部分切除加延长术能够使患者恢复正常排尿功能,减轻患者术后疼痛感,且有利于改善患者负性情绪,促进患者生活质量的提升。

Objective To investigate the clinical effect of partial penectomy and penile lengthening in the treatment of early penile cancer.Methods A total of 50 patients with early penile cancer admitted to our hospital from January 2018 to January 2020 were divided into two groups by random number table.Twenty-five cases in the control group underwent total penile resection,and 25 cases in the study group underwent partial penectomy and penile lengthening.The operation time,intraoperative blood loss,postoperative pain score,postoperative tumor recurrence,incision infection,external urethral stenosis,urination,preoperative and postoperative SAS score,and SDS score were compared between the two groups.Results The operation time of the study group was longer than that of the control group.The amount of intraoperative blood loss of the study group was higher than that of the control group,and the postoperative pain score was lower than that of the control group.The difference was statistically significant,P<0.05.There was no tumor recurrence,incision infection or external urethral stenosis in the two groups after the operation.The control group cooperated with the urethral perineum fistula after the operation,and the patients squatted to urinate normally.The study group stood to urinate normally after the operation,and the voiding function was not affected.The preoperative SAS score and SDS score of the two groups were significantly different between the two groups(P>0.05).The SAS score(48.3±4.5)and SDS score(52.2±4.0)of the postoperative study group were lower than those of the control group[(64.2±5.8)and(63.3±4.8)].The difference was statistically significant(t=10.830,t=8.883,P<0.05).Conclusion In the clinical treatment of early penile cancer,partial penectomy,and penile lengthening can restore normal urination function,reduce postoperative pain,improve the negative emotion of patients and promote the improvement of patients′quality of life.