小儿热速清糖浆治疗手足口病患儿的临床效果

Clinical effect of Xiaoer Resuqing syrup on children with hand-foot-mouth disease

目的 探究观察小儿热速清糖浆对手足口病患儿临床疗效的影响。方法 收集2019年9月至2020年9月本院收治的100例手足口病患儿,按照不同治疗方案将100例患儿分为观察组(小儿热速清糖浆治疗+常规治疗,n=50例)、对照组(常规治疗,n=50例),记录比较两组临床治疗效果、临床症状消失时间、C反应蛋白(C-reaction protein,CRP)水平、降钙素原(procalcitonin,PCT)水平,并进行比较。结果 观察组患儿的临床治疗有效率为98.0%,优于对照组的76.0%,差异有统计学意义(P<0.05)。观察组患儿的发热、口痛、皮疹、厌食临床症状消失时间[(1.57±0.45)d、(3.14±0.71)d、(4.01±1.04)d、(1.91±0.61)d]均短于对照组[(3.71±0.67)d、(5.02±0.86)d、(5.64±1.26)d、(3.65±0.81)d],差异有明显统计学意义(P<0.001),且观察组治疗后CRP、PCT水平[(1.16±0.21)mg/L、(0.31±0.06)ng/mL]均低于对照组[(2.32±0.39)mg/L、(0.56±0.08)ng/mL](P<0.001)。结论 采用小儿热速清糖浆治疗手足口病患儿,临床治疗效果显著,使患儿的临床症状消失时间更短,可有效降低患儿CRP、PCT含量,更具应用价值。

Objective To explore the clinical effect of Xiaoer Resuqing syrup in children with hand-foot-mouth disease.Methods A total of 100 children with hand-foot-mouth disease admitted to our hospital from September 2019 to September 2020 were selected and divided into the observation group(Xiaoer Resuqing syrup combined with conventional treatment,n=50)and the control group(conventional treatment,n=50)according to different treatment regimens.The clinical effect,disappearance time of clinical symptoms,C-reactive protein(CRP)level,and procalcitonin(PCT)level were recorded and compared between the two groups.Results The clinical treatment effect of the observation group was 98.0%,which was better than 76.0%of the control group,and the difference was significant(P<0.05).The disappearance time of clinical symptoms of fever,mouth pain,rash,and anorexia in the observation group([1.57±0.45]d,[3.14±0.71]d,[4.01±1.04]d,[1.91±0.61]d)was shorter than that in the control group([3.71±0.67]d,[5.02±0.86]d,[5.64±1.26]d,[3.65±0.81]d),and the difference was significant(P<0.001).The levels of CRP and PCT in the observation group after treatment([1.16±0.21]mg/L,[0.31±0.06]ng/mL)were lower than those in the control group([2.32±0.39]mg/L,[0.56±0.08]ng/mL)(P<0.001).Conclusion Xiaoer Resuqing syrup in the treatment of Children with hand-foot-mouth disease has a significant clinical therapeutic effect,which makes the disappearance time of clinical symptoms in children shorter,and the contents of CRP and PCT in children effectively reduced,which had more application value.