社区高龄老人贫血患病率的系统综述与Meta分析

Prevalence of anemia in community-based oldest-old population:a systematic review and meta-analysis

目的系统评价我国≥80岁社区高龄老人贫血的患病率。方法检索万方、中国知网、中国生物医学文献数据库、维普中文科技期刊等中文数据库和PubMed、Cochrane图书馆、Embase等英文数据库,搜集关于我国社区高龄老人贫血患病率的研究。由两名研究者独立筛选文献,提取资料并评价纳入研究的偏倚风险后,采用R4.02软件中meta包进行Meta分析。结果最终纳入8个研究,49324名调查对象,其中包括6123名≥80岁社区高龄老人。Meta分析结果显示,我国社区高龄老人贫血患病率为30.0%(20.1%~43.0%),其中男性为32.9%(21.1%~47.4%),女性为24.7%(14.1%~39.6%)。按年龄分组,80~89岁、90~99岁和百岁老人贫血患病率分别为28.5%(15.3%~46.9%),44.3%(30.4%~59.2%)和63.1%(51.5%~73.4%)。结论我国社区高龄老人贫血患病率较高,随年龄增长不断增高,应重点关注。

Objective To systematically review the epidemiological characteristics of anemia in Chinese community-based oldest-old population(≥80 years).Methods The literature review was conducted by using Wanfang Data,China National Knowledge Infrastructure(CNKI),China Biology Medicine(CBM),VIP,PubMed,Cochrane Library and Embase database.Two reviewers independently screened and extracted literature data,then assessed quality of included studies.Meta package in R4.02 software was used to perform meta-analysis.Results A total of 8 studies involving 49324 patients were included.The results of meta-analysis showed that the prevalence of anemia in in Chinese community-based oldest-old population was 30.01%(95%CI 20.05%to 43.00%),in which 32.92%(95%CI 21.06%to 47.43%)was male and 24.69%(95%CI 14.09%to 39.60%)was female.The prevalence of anemia was 28.52%(95%CI 15.27%to 46.90%)in the elderly aged 80 to 89,44.31%(95%CI 30.38%to 59.20%)in the elderly aged 90 to 99,and 63.11%(95%CI 51.45%to 73.42%)in centenarians.Conclusion The prevalence of anemia is high in Chinese community-based oldest-old population,which should be attached more importance in the prevention and control anemia.