甘肃省康县糖尿病及糖调节受损流行现状调查及相关危险因素分析

The epidemiological investigation and risk factors analysis of diabetes mellitus and impaired glucose regulation from Kang county in Gansu province

目的对甘肃省康县城乡居民进行糖尿病及糖调节受损(IGR)流行病学调查,并分析其相关危险因素,为基层糖尿病的防治提供依据。方法于2019年5—11月,采用分层整群随机抽样的方法,将康县4个自然村和3个社区居住5年以上的18~74岁居民作为调查对象,内容包括问卷调查、体格检查和口服葡萄糖耐量试验(OGTT):分别在调查对象禁食8 h后次日清晨和口服75 g葡萄糖2 h后,抽取静脉血标本5 ml,测定空腹以及餐后2 h血糖(2 hPG),对可能影响糖尿病发生的危险因素进行单因素描述和多因素分析。结果康县糖尿病和IGR患病率分别为8.12%、14.15%;城区糖尿病及IGR患病率分别为10.94%、15.84%(P=0.030),农村分别为6.51%、11.94%(P=0.021)。年龄、体重指数、城市居住、性别、糖尿病家族史,高血压、吸烟、高盐饮食和大量饮酒是糖尿病和IGR的危险因素(OR=8.960、7.275、5.431、6.472、5.628、5.233、4.529、3.641、2.773)。结论康县糖尿病和IGR患病率较高,应积极控制体重。

Objective To provide basis for improving the management of diabetes mellitus(DM),the epidemiological characteristics were investigated and its risk factors of DM and impaired glucose regulation(IGR),which from urban and rural residents in Kang county were analysed.Methods From May to November 2019,the residents of 18-74 years old living in the 4 rurals and 3 communities of Kang county for 5 or more years were selected by cluster random sampling method.The study included questionnaires,physical examinations and oral glucose tolerance test(OGTT):5 ml venous blood samples were extracted the next morning after fasting for 8 hours and 2 hours after oral administration of 75 g glucose;fasting and 2 hours postprandial blood glucose(2 hPG)were measured.Results The prevalence of DM and IGR were accounted for 8.12%and 14.15%,respectively.And the prevalence of DM and IGR in the communities was 10.94%and 15.84%(P=0.030),while that in the rural area was 6.51%and 11.94%,respectively(P=0.021).Age,body mass index(BMI),gender,family history of DM,city living,hypertension,smoking,high sodium intake and drinking are all the risk factors of DM and IGR(OR=8.960,7.275,5.431,6.472,5.628,5.233,4.529,3.641,2.773).Conclusion The prevalence of DM and IGR in Kang county is high;Residents in this area need to control their body weight.