新型冠状病毒对男性生殖的损伤及机制

SARS-CoV-2 damages male fertility:How and why

男性生殖系统具有被SARS-CoV-2病毒侵入的结构基础。现有证据表明,SARS-CoV-2会对男性睾丸组织产生实质性损害,引起男性患者睾酮水平下降、黄体生成素上升,精子产生减少、质量降低。睾丸局部炎症、细胞因子风暴和发热,是目前认为可能导致睾丸损伤的潜在机制。新型冠状病毒传播力强,其对男性生殖系统的影响值得关注。

The male reproductive system has a structural basis for being invaded by the SARS-CoV-2 virus.Existing evidence shows that SARS-CoV-2 can cause substantial damage to testicular tissues,pituitary-testicular axis hormone homeostasis,and production and quality of sperm in male patients.Local inflammation of the testis,cytokine storm and fever are considered to be the potential pathogenic factors for testis injury.COVID-19,as a rapidly spreading disease,requires close attention for its impact on the male reproductive system.