肝门部胆管癌术后肝衰竭的研究进展

Research advances of liver failure after surgery for hilar cholangiocarcinoma

肝门部胆管癌是一种预后较差的恶性肿瘤,手术是目前被证明唯一有效的治疗方式,但术后肝衰竭是最严重的术后并发症,也是制约病人生存的重要影响因素之一。因此,探究术后肝衰竭的原因以及预防措施是胆道外科的热点问题。作者通过阅读国内外相关文献,从多个方面对肝门部胆管癌根治术后出现肝衰竭进行了综述。

Hilar cholangiocarcinoma(HC)is a malignant tumor with a poor prognosis.Surgery is a sole effective treatment.However,postpatectomy liver failure(PHLF)has been the most serious postoperative complication and one of the most important prognostic factors.Thus exploring the causes of PHLF and implementing preventive measures has become a hot research topic in biliary surgery.PHLF after radical resection of HC was summarized from many aspects through browsing the relevant domestic and foreign literatures。