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Decreased inhibition of exosomal miRNAs on SARS-CoV-2 replication underlies poor outcomes in elderly people and diabetic patients 被引量:1

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摘要 Elderly people and patients with comorbidities are at higher risk of COVID-19 infection,resulting in severe complications and high mortality.However,the underlying mechanisms are unclear.In this study,we investigate whether miRNAs in serum exosomes can exert antiviral functions and affect the response to COVID-19 in the elderly and people with diabetes.
出处 《Signal Transduction and Targeted Therapy》 SCIE CSCD 2021年第9期2822-2830,共9页 信号转导与靶向治疗(英文)
基金 This work was supported by the Chinese Science and Technology Major Project of China(2015ZX09102023-003) National Basic Research Program of China(973 Program)(2014CB542300 and 2012CB517603) National Natural Science Foundation of China(81250044,81602697,32000549 and 31741075) Training Program of the Major Research Plan of the National Natural Science Foundation of China(92049109) the Natural Science Foundation of Jiangsu Province(BE2016737) the Fundamental Research Funds for the Central Universities(020814380146).
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