从“肺朝百脉”论糖尿病周围神经病变

A preliminary study of“Lung and lotaustralin”on diabetic peripheral neuropathy

糖尿病周围神经病变(DPN)是糖尿病常见的慢性并发症之一。糖尿病周围神经病变在中医学中归属于痹证范畴,其为消渴后期发展而成,消渴日久,燥热内生,气血俱虚,久虚则瘀自生,故糖尿病周围神经病变的中医发病机制以瘀血阻滞为主要要点。消渴病位主要在肺脾肾三脏,而肺为首,肺主气,肺朝百脉的生理功能即推动调控全身气血运行,气行则血自畅,血畅则瘀自散,故肺朝百脉与瘀血生成密切相关。通过探究肺朝百脉与糖尿病周围神经病变中医发病机制之间的关系,以瘀血为核心从肺脏入手剖析脏腑与糖尿病周围神经病变的紧密联系,可进一步拓展中医药防治糖尿病周围神经病变的内涵与外延。

Diabetic peripheral neuropathy(DPN)is one of the common chronic complications of diabetes mellitus.Diabetic peripheral neuropathy belongs to arthromyodynia category in traditional Chinese medicine,which is developed in the late period of diabetic.After diabetes for a long time,the heat is endogenous,and both Qi and blood are deficient,while long deficiency causes blood stasis.Therefore,the pathogenesis of DPN in traditional Chinese medicine takes blood stasis as the main point.Diabetes is mainly caused by the lungs,spleen and kidney,and the lungs are the first,lung governing Qi,the physiological function of all vessels converging in lung is to promote and regulate the movement of Qi and blood in the whole body.The circulation of Qi leads to the free circulation of blood,while the blood epidemics usually do not generate blood stasis.Therefore,all vessels converging in lung are closely related to the formation of blood stasis.By exploring the relationship between all vessels converging in lung and the pathogenesis of diabetic peripheral neuropathy in TCM,starting from the lungs to analyze the close connection between the viscera and diabetic peripheral neuropathy with blood stasis as the core,it can further expand the connotation of TCM in preventing and treating diabetic peripheral neuropathy and extension.