下颌下腺多形性腺瘤复发伴双侧多发肺转移一例

Recurrent pleomorphic adenoma of submandibular gland with bilateral multiple pulmonary metastasis:A case report

多形性腺瘤是唾液腺肿瘤中最为常见的良性肿瘤,极少发生转移,临床及组织病理学将远处转移者称为转移性多形性腺瘤(MPA)。本文报道一例罕见的原发于下颌下腺的多形性腺瘤,术后复发伴双肺多发转移。给予患者下颌下腺区及肺部肿物联合手术切除术。现通过文献复习,分析该类疾病的临床病理特征、转移特点及治疗的策略要点。

Pleomorphic adenoma is the most common benign tumor in salivary gland and its metastasis rarely occurs. The local or distant metastatic tumor of benign pleomorphic adenoma is clinically and histopathologically called metastatic pleomorphic adenoma(MPA). A rare case of pleomorphic adenoma was reported in this article. This patient suffered from a pleomorphic adenoma originally in the left submandibular gland,which was treated by surgical removal two years ago. Subsequently,a local recurrence of the pleomorphic adenoma with multiple bilateral pulmonary metastasis was found,so that the submaxillary area and lung masses were surgically exenterated. Upon the review of literature,the clinicopathological and metastatic features,as well as the key therapeutic strategies of this disease were discussed in this article.