2013—2017年黑龙江省肿瘤登记地区膀胱癌发病与死亡分析及时间变化趋势

Incidence and mortality of bladder cancer in cancer registration areas of Heilongjiang province in 2013—2017

目的分析2013—2017年黑龙江省肿瘤登记地区膀胱癌发病与死亡情况及时间变化趋势。方法收集2013—2017年黑龙江省肿瘤登记地区上报的膀胱癌发病与死亡病例资料,计算发病(死亡)率、标化发病(死亡)率、累积率(0~74岁)等,标化率采用2000年全国人口普查标准人口构成和Segi’s世界标准人口构成作为标准。年度变化百分比(APC)使用JoinPoint软件计算。结果2013—2017年黑龙江省肿瘤登记地区膀胱癌发病率为6.16/10万,中标率为3.48/10万,累计率(0~74岁)为0.39%;其中男性发病率(9.29/10万)高于女性(3.09/10万),城市地区发病率(7.11/10万)高于农村地区(3.80/10万)。2013—2017年黑龙江省肿瘤登记地区膀胱癌死亡率为2.77/10万,中标率为1.49/10万,累积率(0~74岁)为0.14%;其中男性死亡率(3.91/10万)高于女性(1.64/10万),城市地区死亡率(3.17/10万)高于农村地区(1.76/10万)。2013—2017年黑龙江省肿瘤登记地区膀胱癌发病中标率呈升高趋势,APC为11.6%,差异有统计学意义(P<0.05),2013—2017年死亡中标率也呈升高趋势,APC为7.3%,但差异无统计学意义(P>0.05)。结论膀胱癌是威胁黑龙江省居民身心健康的恶性肿瘤之一,应对高风险人群做好积极防治工作。

ObjectiveTo analyze the trend of incidence,mortality and time of bladder cancer in cancer registration areas of Heilongjiang province from 2013 to 2017.MethodsThe incidence(mortality)rate,age-standardized incidence(mortality)rate and cumulative rate(0~74 years old)of bladder cancer in Heilingjiang cancer registration areas from 2013 to2017 were calculated.Chinese population census in 2000 and World Segis standard population were used for age-standardized.Annual percentage change(APC)was calculated by JoinPoint software.ResultsFrom 2013 to 2017,the incidence of bladder cancer in the cancer registration areas of Heilongjiang province was 6.16/105,the age-standardized incidence rate by Chinese standard population(ASR China)was 3.48/105,and the cumulative rate(0~74 years old)was 0.39%.The incidence of bladder cancer in males(9.29/105)was higher than that in females(3.09/105).The incidence of bladder cancer in urban areas(7.11/105)was higher than that in rural areas(3.80/105).From 2013 to 2017,the mortality rate of bladder cancer was 2.77/105,ASR China mortality was 1.49/105,and the cumulative rate(0~74 years old)was 0.14%in the cancer registration areas of Heilongjiang province.The mortality rate of bladder cancer in males(3.91/105)was higher than that in females(1.64/105).The mortality rate of bladder cancer in urban areas(3.17/105)was higher than that in rural areas(1.76/105).The ASR China incidence showed an up-trend between 2013 and 2017,with APC of 11.6%(P<0.05).The ASR China mortality also increased,with APC of 7.3%,but the difference was not statistically significant(P>0.05).ConclusionBladder cancer is one of the malignant tumors threatening the physical and mental health of residents in Heilongjiang province.Active prevention and treatment should be carried out for high-risk groups.