肥胖儿童性早熟的相关危险因素分析研究

Risk Factors of Precocious Puberty in Obese Children

目的将我院确诊的肥胖儿童性早熟患儿为观察对象,分析造成肥胖儿童性早熟病症的相关危险因素。方法抽选我院门诊确诊的性早熟肥胖儿童78例为观察组,抽选同时期的健康儿童78例为对照组,对两组研究对象实施体格与实验室检查、问卷调查等措施,依据临床各项检查与调查的结果,分析其相关危险因素。时间为2019年1月-2020年4月。结果经分析,观察组女性患儿所占比例为84.62%,而对照组女性儿童所占比例为33.33%,观察组远高于对照组,差异有统计学意义(P<0.05);观察组出生体质量、母亲初潮年龄分别为(3.26±1.01)kg、(13.56±0.74)岁,对照组分别为(2.86±1.02)kg、(14.26±0.65)岁,组间数据比较有差异意义(P<0.05);同时观察组患儿偏好营养滋补品、激素高、反季节与添加剂较高等食物的比例为56.41%、20.51%、23.08%、26.92%,对照组的26.92%、7.69%、8.97%、11.54%,差异有统计学意义(P<0.05),而两组高蛋白质食物比例比较差异无统计学意义(P>0.05)。结论据统计,肥胖儿童的内分泌系统异常、饮食习惯较差、遗传等因素的影响,增大了性早熟发生的风险,因此积极帮助儿童养成良好的饮食习惯,可有效降低儿童性早熟的发生率。

Objective To analyze the risk factors of the disease in our hospital.Methods 78 obese children diagnosed in our clinic were selected as observation groups,and 78 healthy children of the same period were selected as control groups.The physical and laboratory examination and questionnaire survey were implemented to the two groups,and the relevant risk factors were analyzed according to the results of clinical examination and investigation.From January 2019-April 2020.Results were analyzed,The proportion of female children in the observation group was 84.62%,The proportion of the control female children was 33.33%,The observation group was much higher than the controls,Differences were statistically significant(P<0.05);The quality of birth and maternal age of menarche were(3.26±1.01)kg,(13.56±0.74)years,respectively,The control group was(2.86±1.02)kg,(14.26±0.65)years old,respectively,Data comparisons were somewhat significant between groups(P<0.05);At the same time,the proportion of children in the observation group preferring nutritional tonic,high hormones,off-season and higher additives was 56.41%,20.51%,23.08%and 26.92%,Control group was 26.92%,7.69%,8.97%,and 11.54%,Differences were statistically significant(P<0.05),However,there was no significant difference in the high protein food ratio between the two groups(P>0.05).Conclusion According to statistics,the influence of abnormal endocrine system,poor eating habits,genetic factors and other factors in obese children increases the risk of precocious puberty,so they actively help children to develop good eating habits,which can effectively reduce the incidence of precocious puberty in children.