摘要
5年前兴起的精确医学已经成为当今国际生物医学领域的一个主要潮流,并正在不断地推动和实践着现代医学史上最重要的变革。精确医学的战略目标是,建立一个重视个体差异,尤其是在分子水平上的个体差异的新型生物医学研究和临床实践体系。首先,精确医学基于分子层面的信息进行了疾病分类新标准的制定;其次,在疾病分类新标准的基础上发展了多种临床研究新模式。更值得强调的是,那些源自临床研究新模式的新型临床证据以及真实世界证据已经用于指导临床实践。
Precision medicine,which was initiated 5 years ago,becomes a mainstream in the area of biomedicine and continuously promotes the evolution of modern medicine.The strategic goal of the precision medicine is to construct a new infrastructure for the biomedical research and clinical care based on personal data and particularly the biomolecular data.First,the precision medicine has generated the new standards for classification of diseases based on biomolecular data.Secondly,new forms of clinical trials have been developed based on the new classification of diseases.Importantly,the new clinical evidences and real world evidence have been used for the clinical practice.
作者
吴家睿
WU Jia-rui(Institute of Biochemistry and Cell Biology,Chinese Academy of Science,Shanghai 200031,China)
出处
《医学与哲学》
北大核心
2021年第20期1-4,10,共5页
Medicine and Philosophy
基金
2020年中国科学院战略先导专项(XDB38000000)。
关键词
精确医学
疾病分类
临床研究
临床证据
precision medicine
classification of diseases
clinical trial
clinical evidence
