长叶纽子果根化学成分的研究

Chemical constituents from Ardisia virens

目的研究长叶纽子果Ardisia virens Kurz var.annamensis Pitard.的化学成分。方法长叶纽子果70%乙醇提取物采用硅胶柱、Sephadex LH-20、ODS、制备HPLC进行分离纯化,根据理化性质及波谱数据鉴定所得化合物的结构。结果从中分离得到9个化合物,分别鉴定为岩白菜素(1)、4-O-(3,5-二甲基没食子酰基)岩白菜素(2)、11-O-没食子酸酰基岩白菜素(3)、11-O-香草岩白菜素(4)、11-O-异香草岩白菜素(5)、11-O-丁香酰基岩白菜素(6)、11-O-(3′,4′-二甲氧基苯甲酰)岩白菜素(7)、百两金皂苷A(8)、邻苯二甲酸二丁酯(9)。结论所有化合物均为首次从该植物中分离得到。

AIM To study the chemical constituents from Ardisia virens Kurz var.annamensis Pitard.METHODS The 70% ethanol extract from A. virens was isolated and purified by silica, Sephadex LH-20, ODS and preparative HPLC,then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESULTS Nine compounds were isolated and identified as bergenin(1),4-O-(3,5-di-methylgalloyl)bergenin(2),11-O-gallaoyl bergenin(3),11-O-vanilloyl bergenin(4),11-O-isovanilloyl bergenin(5),11-O-syringl bergenin(6),11-O-(3′,4′-dimethoxy benzoyl)bergenin(7),ardisia crispa A(8),dibutyl phthalate(9).CONCLUSION All the compounds are isolated from this plant for the first time.