根管光活化消毒技术对根管内优势致病菌的杀灭效果

Analysis of the killing effect of root canal photo-activated disinfection on dominant pathogenic bacteria in root canal

目的:研究根管光活化消毒(PAD)技术对根管内优势致病菌的杀灭效果。方法:将100例慢性根尖周炎患者分成观察组(n=50)和对照组(n=50),每组各50例。两组均接受常规根管治疗,观察组在根管预备前和氢氧化钙封药后分别进行PAD技术消毒根管。分析根管治疗前后疼痛程度、根尖区病损牙槽骨密度、菌落总数及牙龈卟啉单胞菌、粪肠球菌检出率的变化,并计算治疗成功率。结果:根管预备后3 d,两组疼痛程度均有减轻,观察组减轻程度大于对照组(P<0.05),观察组从约诊间痛(EIAP)发生率低于对照组(42.00%vs.60.00%,P>0.05);治疗3个月后,观察组患齿菌落总数以及牙龈卟啉单胞菌、粪肠球菌检出率均低于治疗前及对照组(P<0.05);观察组根尖区病损牙槽骨密度均高于治疗前及对照组(P<0.05),观察组成功率高于对照组(96.00%vs.84.00%,P<0.05)。结论:根管PAD技术可有效缓解慢性根尖周炎患者的疼痛,降低菌落总数及优势致病菌检出率,改善根尖区病损牙槽骨密度,提高治疗的成功率。

Objective:To analyze the killing effect of root canal photo-activated disinfection(PAD)on dominant pathogenic bacteria in root canal.Methods:A total of 100 patients with chronic periapical periodontitis were selected as the research objects,they were divided into observation group(n=50)and control group(n=50).Both groups received conventional root canal therapy,and the observation group received PAD before root canal preparation and after calcium hydroxide seal,respectively.The changes of pain degree,bone mineral density,the total number of colonies and the detection rate of porphyromonas gingivalis and enterococcus faecalis were analyzed before and after root canal treatment,and the success rate of treatment was calculated.Results:3 days after root canal preparation,the pain degree of both groups was relieved,and the relief degree of observation group was greater than control group(P<0.05),the incidence of EIAP in the observation group was lower than that in the control group(42.00%vs.60.00%,P>0.05).After 3 months of treatment,the total number of colonies and the detection rates of Porphyromonas gingivalis and Enterococcus faecalis in the observation group were lower than those before treatment and in the control group(P<0.05).The alveolar bone density of the observation group was higher than that before treatment and the control group(P<0.05),and the success rate of the observation group was higher than that of the control group(96.00%vs.84.00%,P<0.05).Conclusion:Root canal PAD technology in chronic periapical inflammation can effectively relieve the pain of patients,reduce the total number of bacterial colonies and the detection rate of dominant pathogens,improve the bone density of the diseased alveolar in the root tip area,and improve the success rate of treatment.