情绪反应性在心境障碍患者早年家庭功能不全与自杀风险间的中介效应

The Mediating Effects of Emotion Reactivity between Early Family Dysfunction and Suicide Risk in Patients with Mood Disorders

目的:探讨情绪反应性在心境障碍患者早年家庭功能不全与自杀风险之间的中介作用。方法:纳入426例心境障碍患者,采用情绪反应性量表(Emotion Reactivity Scale,ERS)、童年不良经历问卷国际版(Adverse Childhood Experiences-International Questionnaire,ACE-IQ)中的家庭功能不全维度和自杀行为问卷-修订版(Suicide Behaviors Questionnaire-Revised,SBQ-R)进行测评。结果:①心境障碍患者的情绪反应性总分及其3个方面(情绪敏感性、情绪强度和情绪持续性)与SBQ-R得分之间呈正相关(r=0.588,P<0.01;r=0.564,P<0.01;r=0.518,P<0.01;r=0.512,P<0.01);②情绪反应性总分在心境障碍患者早年家庭功能不全与自杀风险之间的中介作用显著(中介效应值=0.21,95%CI=0.12~0.30);情绪反应性的3个方面(情绪敏感性、情绪强度和情绪持续性)在心境障碍患者早年家庭功能不全与自杀风险之间的中介作用均显著(中介效应值=0.10,95%CI=0.04~0.19;中介效应值=0.06,95%CI=0.01~0.13;中介效应值=0.04,95%CI=0.01~0.09)。结论:情绪反应性及其3个方面在心境障碍患者早年家庭功能不全与自杀风险之间存在中介作用。

Objective:To explore the mediating effects of emotion reactivity on the relationship between early family dysfunction and suicide risk in patients with mood disorders.Methods:426 patients with mood disorders were included in this cross-sectional study,and the Emotion Reactivity Scale(ERS),family dysfunction subscale of the Adverse Childhood Experiences-International Questionnaire(ACE-IQ)and the Suicide Behaviors Questionnaire-Revised(SBQ-R)were completed.Results:①The scores of ERS and its three aspects(emotional sensitivity,intensity and persistence)were positively correlated with the score of SBQ-R in patients with mood disorders;②The total score of ERS played a mediating role between early family dysfunction and SBQ-R(indirect effect=0.21,95%CI=0.12~0.30);three aspects of ERS(emotional sensitivity,intensity,and persistence)played a mediating role between early family dysfunction and SBQ-R in patients with mood disorders(indirect effect=0.10,95%CI=0.04~0.19;indirect effect=0.06,95%CI=0.01~0.13;indirect effect=0.04,95%CI=0.01~0.09).Conclusion:The ERS and its three aspects exert mediation effects on the relationship between early family dysfunction and SBQ-R in patients with mood disorders.