原发性高血压患者并发高尿酸血症的危险因素分析

Analysis of risk factors of hyperuricemia in patients with essential hypertension

目的:探讨原发性高血压(EHT)患者并发高尿酸血症(HUA)的危险因素。方法:回顾性分析2019年6月至2020年6月该院收治的97例EHT患者的临床资料,统计其HUA发生情况,对可能导致HUA的危险因素进行单因素分析和Logistic回归分析。结果:97例EHT患者中,并发HUA 30例(30.93%);单因素分析和Logistic回归分析显示,年龄≥60岁、男性、饮酒、合并2型糖尿病、体质量指数≥24 kg/m^(2)、总胆固醇≥5.69 mmol/L、三酰甘油≥1.70 mmol/L均为EHT患者并发HUA的独立危险因素(P<0.05)。结论:年龄≥60岁、男性、饮酒、合并2型糖尿病、体质量指数≥24 kg/m^(2)、总胆固醇≥5.69 mmol/L、三酰甘油≥1.70 mmol/L均为EHT患者并发HUA的独立危险因素,临床需针对上述因素采取干预措施,以降低HUA发生率。

Objective:To explore risk factors of hyperuricemia(HUA)in patients with essential hypertension(EHT).Methods:The clinical data of 97 EHT patients admitted to our hospital from June 2019 to June 2020 were retrospectively analyzed,and the occurrence of HUA was statistically analyzed.The univariate analysis and Logistic regression analysis were performed on the risk factors that may lead to HUA.Results:Among the 97 EHT patients,30(30.93%)were complicated by HUA.The univariate analysis and Logistic regression analysis showed that age≥60 years old,male,drinking,type 2 diabetes,body mass index≥24 kg/m^(2),total cholesterol≥5.69 mmol/L,and triglyceride≥1.70 mmol/L were all the independent risk factors for HUA in the EHT patients(P<0.05).Conclusions:Age≥60 years old,male,drinking,type 2 diabetes,body mass index≥24 kg/m^(2),total cholesterol≥5.69 mmol/L,and triglyceride≥1.70 mmol/L are all the independent risk factors for HUA in the EHT patients.Therefore,the clinical interventions are targeted for the above factors so as to reduce the incidence of HUA.