摘要
1例2岁左肾母细胞瘤男性患儿因不能进食,在行根治性左肾切除术前给予肠外营养支持治疗(含中/长链脂肪乳注射液、ω‑3鱼油脂肪乳注射液等)。治疗前血生化检查示三酰甘油(TG)1.18 mmol/L、总胆固醇(TC)2.68 mmol/L、高密度脂蛋白胆固醇(HDL‑C)0.80 mmol/L、低密度脂蛋白胆固醇(LDL‑C)1.48 mmol/L。治疗7 d后血生化检查示TG 4.28 mmol/L、TC 5.48 mmol/L、HDL‑C 1.32 mmol/L、LDL‑C 3.74 mmol/L。考虑为过度肠外营养导致的血脂代谢紊乱。停用中/长链脂肪乳注射液,2 d后复查血生化,TG 3.34 mmol/L、TC 3.17 mmol/L、HDL‑C 0.86 mmol/L、LDL‑C 2.67 mmol/L;7 d后,血生化各项指标均恢复正常。
A 2‑year‑old boy with left nephroblastoma was treated with parenteral nutrition(including medium/long chain fat emulsion injection,ω‑3 fish oil fat emulsion injection,etc.)before radical left nephrectomy because he was unable to eat.The blood biochemical tests before treatment showed triacylglycerol(TG)1.18 mmol/L,total cholesterol(TC)2.68 mmol/L,high density lipoprotein cholesterol(HDL‑C)0.80 mmol/L,and low density lipoprotein cholesterol(LDL‑C)1.48 mmol/L.After 7 days of treatment,blood biochemical tests showed TG 4.28 mmol/L,TC 5.48 mmol/L,HDL‑C 1.32 mmol/L,and LDL‑C 3.74 mmol/L.Dyslipidemia caused by excessive parenteral nutrition was considered.Medium/long chain fat emulsion injection was stopped.Two days later,the blood biochemistry tests showed TG 3.34 mmol/L,TC 3.17 mmol/L,HDL‑C 0.86 mmol/L,and LDL‑C 2.67 mmol/L;7 days later,all blood biochemical indexes returned to normal.
作者
史金平
李薇
Shi Jinping;Li Wei(Department of Pharmacy,Xi′an International Medical Center Hospital,Xi′an 710100,China)
出处
《药物不良反应杂志》
CSCD
2021年第10期559-560,共2页
Adverse Drug Reactions Journal
关键词
胃肠外营养
血脂异常
Parenteral nutrition
Dyslipidemia
