联合筋膜鞘悬吊术与额肌瓣悬吊术矫正重度上睑下垂的Meta分析

Clinical effects of conjoint fascial sheath suspension and frontalis muscle flap suspension in correction of severe blepharoptosis:a Meta-analysis

目的评估联合筋膜鞘悬吊术与额肌瓣悬吊术矫正重度上睑下垂的效果。方法通过检索中国知网(CNKI)、维普期刊7.0系统(VIP)、万方数据知识服务平台、Pubmed、Cochrane图书馆、Web of Science数据库(SCIE)等数据库,收集各数据库2002年2月至2019年4月联合筋膜鞘悬吊术与额肌瓣悬吊术矫正重度上睑下垂的相关研究,对两种手术的矫正有效率、并发症发生率、复发率进行Meta分析。结果最终纳入7篇随机对照研究,共纳入315例患者387只眼,联合筋膜鞘悬吊术组158例192只眼;额肌瓣悬吊术组157例195只眼。联合筋膜鞘悬吊术矫正有效率高于额肌瓣悬吊术,差异有统计学意义(P<0.05),联合筋膜鞘悬吊术并发症发生率和复发率低于额肌瓣悬吊术,差异有统计学意义(P<0.05)。结论联合筋膜鞘悬吊术矫正重度上睑下垂的效果优于额肌瓣悬吊术。

Objective To evaluate the clinical effects of conjoint fascial sheath suspension and frontalis muscle flap suspension in correction of severe blepharoptosis.Methods The databases of China National Knowledge Infrastruction(CNK),WANGFANG DATA,VIP,PubMed,Cochrane Library and Web of Science(SCIE)databases were searched.All relevant studies were collected from February 2002 to April 2019,and the clinical effects of conjoint fascial sheath suspension and frontalis muscle flap suspension in correction of severe blepharoptosis were studied.The correction effective rate,complication rate and recurrence rate between two operations were Meta analyzed.Results A total of seven randomized controlled trial studies including 387 eyes of 315 patients were subject to final analysis.The conjoint fascial sheath suspension group had 158 patients(192 eyes)and frontalis muscle flap suspension group had 157 patients(195 eyes).The results showed that the correction effective rate of conjoint fascial sheath suspension was higher than frontalis muscle flap suspension.There were statistically significant difference between the two groups(P<0.05).The rate of complication and recurrence were lower.There were statistically significant difference between the two groups(P<0.05).Conclusions The clinical effects of conjoint fascial sheath suspension are better than frontalis muscle flap suspension in correction of severe blepharoptosis.