男性慢性肝病患者勃起功能障碍研究进展

Erectile dysfunction in male patients with chronic liver diseases

目的肝脏是性激素、脂质等多种物质代谢的重要器官。男性慢性肝病患者常合并性激素代谢紊乱、糖脂代谢紊乱和精神心理疾病等,容易发生勃起功能障碍,对患者的身心健康和家庭生活造成影响。现有研究表明,男性慢性肝病患者勃起功能障碍患病率在24.6%~85.0%之间,慢性肝炎患者勃起功能障碍患病率为8.6%~78.0%,而肝硬化患者勃起功能障碍患病率为41.2%~92.0%。本文对男性慢性肝病患者发生勃起功能障碍的发病状况、影响因素、可能的发病机制和治疗研究进展进行综述,期望引起广泛的关注,改善患者的身心健康。

Objective Liver is an important organ for the metabolism of sex hormones,lipids and other substances.Male patients with chronic liver disease often suffer from a variety of dysfunctions,such as sex hormone metabolism,glucose and lipid metabolism and mental and psychological disorder.Erectile dysfunction is easy to occur,which affects the physical and mental health and the family life of patients.Existing studies have shown that the prevalence of male erectile dysfunction in patients with chronic liver disease was 24.6%to 85%,the prevalence in chronic hepatitis patients was 8.6%to 78%,and in patients with cirrhosis was 41.2%to 92%.In this paper,we reviewed the incidence,impacting factors,possible pathogenesis,and treatment of erectile dysfunctions in male patients with chronic liver disease.