血清25羟基维生素D与2型糖尿病相关性分析

Analysis of the relationship between 25-hydroxy-vitamin D and type 2 diabetes mellitus

目的:探讨血清25-羟基维生素D水平与2型糖尿病之间的相关性及临床意义。方法:选取2019年1月~2020年4月收治的122例2型糖尿病非骨质疏松患者作为观察组,并选取同期收治的66例骨质疏松非糖尿病患者为对照A组和体检中心的40例健康体检者为对照B组,对三组人群的血清25-羟基维生素D水平进行观察分析。结果:三组血清25-羟基维生素D水平均数不同,观察组和对照A组均数均低于对照B组,差异有统计学意义(P<0.01),但观察组与对照A组均数差异无统计学意义(P>0.05)。结论:2型糖尿病患者血清25-羟基维生素D水平明显缺乏,其程度与骨质疏松相当。

Objective This study aimed to investigate the relationship and clinical significance between serum 25 hydroxyvitamin D level(osteoporosis)and type 2 diabetes.Method From January 2019 to April 2020,122 non osteoporosis patients with type 2 diabetes admitted to our hospital were selected as the observation group,66 osteoporosis patients with no diabetes(control group A)admitted to our hospital in the same period and 40 healthy people(control group B)in the physical examination center were selected as the control group.The serum 25 hydroxyvitamin D levels of the three groups were observed and analyzed.Results The mean value of serum 25 hydroxyvitamin D in three groups was different.The mean value of observation group and control group A was lower than that of control group B(P<0.01),but there was no statistical difference between observation group and control group A(P>0.05).Conclusion The level of serum 25 hydroxyvitamin D in type 2 diabetic patients was significantly deficient,which was similar to that in osteoporosis group.