老年慢性创面动物模型的建立及研究进展

Establishment and Research Progress of Animal Model of Chronic Wound in Elderly

在全球老龄化的大环境下,慢性创面在老年群体中的患病率不断升高,为了更好地探索常见老年慢性创面的发病机制及更有效地诊疗手段,需要建立适宜的动物模型。本文对压迫性溃疡创面、静脉性溃疡创面及糖尿病足创面三大占比较高的慢性创面疾病的动物模型建立方式、存在问题和未来发展进行概述。

In the global environment of aging,the prevalence of chronic wounds in the elderly population is increasing.In order to better explore the pathogenesis of common chronic wounds in the elderly and more effective means of diagnosis and treatment,appropriate animals need to be established.This article summarizes the three animal disease models with high compressive ulcer wounds,venous ulcer wounds,and diabetic foot wounds,as well as their existing problems and future development.