摘要
高脂血症的发生主要受遗传和环境因素的影响,可直接引起动脉粥样硬化、糖尿病和脂肪肝等疾病的发生,危害人体的健康。文章综述了食用菌多糖降脂作用的研究现状,总结了食用菌多糖通过抑制总胆固醇合成途径,促进胆汁酸合成,调控脂代谢相关因子表达,减轻氧化应激反应和调节肠道功能等途径改善高脂血症的作用机制,并对食用菌多糖用于高脂血症的治疗前景进行了展望。旨在为食用菌多糖预防高脂血症及食用菌功能产品的研发提供理论参考。
Hyperlipoidemia is mainly affected by the heredity and environment,and the onset of several diseases,such as diabetes,liver diseases,and atherosclerosis.This paper reviews the research status of lipid-lowering effect of edible fungus polysaccharide,summarizes the mechanism of edible fungus polysaccharide improving hyperlipidemia by inhibiting the synthesis of total cholesterol,promoting bile acid synthesis,regulating the expression of lipid metabolism related factors,reducing oxidative stress response and regulating intestinal function,and looks forward to the prospect of edible fungus polysaccharide in the treatment of hyperlipidemia.The purpose is to provide theoretical reference for the prevention of hyperlipidemia and the research and development of functional products of edible fungi.
作者
魏奇
翁馨
吴艳钦
张锶莹
张维瑞
刘盛荣
韩坤煌
陈美霞
WEI Qi;WENG Xin;WU Yanqin;ZHANG Siying;ZHANG Weirui;LIU Shengrong;HAN Kunhuang;CHEN Meixia(College of Life Science,Ningde Normal University,Ningde 352100,China;Engineering Research Center,Fujian Provincial University,Ningde 352100,China;Engineering Research Center of Mindong Aquatic Product Deep-Processing,Fujian Province University,Ningde 352100,China;Industry and University Research Cooperation Demonstration Base in Fujian Provice,Ningde 352100,China)
出处
《食品科技》
CAS
北大核心
2021年第9期190-194,共5页
Food Science and Technology
基金
宁德师范学院引进人才科研启动项目(2020Y010)
宁德师范学院重大培育项目(2020ZDK03)
福建省中青年教师教育科研项目(JAT200689)
宁德师范学院校级项目(2020Z01,2019T02)。
关键词
食用菌
多糖
降脂
作用机制
edible fungus
polysaccharides
hypolipidemic
mechanism
