阿尔茨海默病循证预防国际指南

Evidence-based prevention guideline of Alzheimer's disease

对阿尔茨海默病循证预防国际指南作了解读。概述了阿尔茨海默病预防的具体策略、人群差异、现状及前景。根据指南,通过健康的生活方式(包括体重管理、体育锻炼、认知活动、良好睡眠、远离烟草等),良好的共病管理(糖尿病、高血压、高同型半胱氨酸血症、心脑血管疾病、头部外伤、抑郁等),提高教育程度以及维生素C摄入等可以预防阿尔茨海默病的发病。

Recently,our paper entitled"evidense-based prevention of Alzheimer's disease"published in Journal of Neurology,Neurosurgery&Psychiatry(JNNP)has attached much attention.In this review,we will discuss the contents of this paper including the prevention strategies,the population difference,the current status and the future prospect of the AD,to guide the clinical practice of the AD primary prevention,such as the healthy lifestyles(the weight control,the physical exercise,the cognitive activity,sufficient and good quality sleep,and staying away from smoking),and the management of comorbidities(the diabetes,the high blood pressure,the hyperhomocysteinaemia,the cardiovascular disorders,the head trauma,and the depression),and it is shown that the high education and the vitamin C intake can reduce the incidence risk of the Alzheimer's disease(AD).