2型糖尿病患者发生小腿肌间静脉血栓的危险因素分析

Analysis of risk factors of calf muscular venous thrombosis in patients with type 2 diabetes mellitus

目的探讨2型糖尿病患者发生小腿肌间静脉血栓的危险因素。方法回顾性分析2012年1月至2021年5月于济南市中医医院内分泌科及滕州市中医医院内分泌科住院治疗的174例2型糖尿病患者的临床资料,根据是否发生小腿肌间静脉血栓分为血栓组与对照组,对比分析两组患者的性别、年龄、体重指数、糖尿病病程等临床资料,进行单因素分析,组间比较有显著差异的单因素,代入二元logistic回归分析进行独立危险因素检验。结果两组患者性别、糖尿病周围血管病变、糖化血红蛋白水平、甘油三酯水平、总胆固醇水平、超敏C反应蛋白水平差异均有统计学意义(P均<0.05)。结论性别、糖尿病周围血管病变、甘油三酯水平、总胆固醇水平、超敏C反应蛋白水平是2型糖尿病患者发生小腿肌间静脉血栓的独立危险因素。

Objective To investigate the risk factors of calf muscular venous thrombosis in patients with type 2 diabetes mellitus.Methods The clinical data of 174 patients hospitalized in the Department of Endocrinology of Jinan Municiple Hospital of Traditional Chinese Medicine and the Department of Endocrinology of Tengzhou Traditional Chinese Medicine Hospital from January 2012 to May 2021 were retrospectively analyzed.The patients were divided into thrombosis group and control group according to the occurrence of calf muscular venous thrombosis,and the clinical data of the two groups,such as age,body mass index,duration of diabetes,were compared and analyzed in a single-factor analysis.The single factors with significant differences between two groups were substituted into binary logistic regression analysis for independent risk factor test.Results Gender,number of patients with diabetic peripheral vasculopathy,level of glycosylated hemoglobin,triglyceride,total cholesterol and high sensitivity C-reactive protein level between two groups were statistically different(all P<0.05).Conclusion Diabetic peripheral vasculopathy and high sensitivity C-reactive protein level are the independent risk factors of calf muscular venous thrombosis in patients with type 2 diabetes mellitus.