摘要
糖尿病肾脏病是糖尿病主要并发症之一,也是终末期肾病的主要原因。铁在人体生命活动中十分重要,大量研究证据都表明,铁代谢与糖尿病肾脏病密切相关。铁、铁蛋白、转铁蛋白、铁调素等这些铁代谢指标都与糖尿病肾脏病发生、发展有着紧密联系。针对铁代谢的干预将会给糖尿病肾脏病的诊疗提供新的方案。
Diabetic kidney disease is one of the main complications of diabetes mellitus and the main cause of end-stage renal disease.Iron plays an important role in human life.A large number of studies have shown that iron metabolism is closely related to diabetic kidney disease.These iron metabolic indicators including(iron,ferritin,transferrin and hepcidin)are closely related to the occurrence and development of diabetic kidney disease.The intervention of iron metabolism will provide a new method for the diagnosis and treatment of diabetic kidney disease.
作者
蒋艺婕
张红
华飞
Jiang Yijie;Zhang Hong;Hua Fei(Department of Endocrinology,The First People's Hospital of Changzhou,The Third Affiliated Hospital of Soochow University,Changzhou 213003,China)
出处
《国际内分泌代谢杂志》
2021年第5期468-471,共4页
International Journal of Endocrinology and Metabolism
基金
常州市卫生人才培养工程资助项目(2016ZCLJ020)。
关键词
铁代谢
糖尿病肾脏病
铁死亡
Iron metabolism
Diabetic kidney disease
Ferroptosis