摘要
急性心肌梗死是临床上最严重的心血管疾病之一,是威胁人类健康的主要杀手。近年来研究发现骨髓干细胞可以分化成心肌细胞和血管内皮细胞,并分泌多种生长因子,因而骨髓干细胞移植替代坏死心肌已经成为目前心肌梗死治疗领域的研究热点。文章对干细胞移植治疗急性心肌梗死的作用机制、研究状况、存在的问题及前景进行综述。
Acute myocardial infarction(AMI),one of the most serious cardiovascular diseases in clinic,is a major threat to human health.Recently,it has been found that bone marrow stem cells can differentiate into cardiomyocytes and vascular endothelial cells,and secrete a variety of growth factors.Therefore,bone marrow stem cell transplantation has become a research hotspot in the field of myocardial infarction treatment.This article reviews the mechanism,research status,existing problems and prospects of stem cell transplantation in the treatment of acute myocardial infarction.
作者
卢文燕
张明
LU Wen-yan;ZHANG Ming(Grade 2018,Medical Department of Graduate School,Nanchang University;Department of General Practice,Jiangxi Provincial People’s Hospital,Nanchang 330006,China)
出处
《南昌大学学报（医学版）》
2021年第5期93-97,共5页
Journal of Nanchang University：Medical Sciences
基金
江西省卫生厅科技计划项目(20185015)。
关键词
骨髓干细胞
移植
间充质干细胞
急性心肌梗死
bone marrow stem cells
transplantation
mesenchymal stem cells
acute myocardial infarction
