康复治疗联合玻璃酸钠关节腔注射治疗膝关节损伤的临床效果

Clinical effect of rehabilitation therapy combined with sodium hyaluronate intraarticular injection in the treatment of knee injury

目的探讨康复治疗联合玻璃酸钠关节腔注射治疗膝关节损伤的临床效果。方法选取福鼎市医院2018年12月—2020年4月收治的膝关节损伤106例,按照患者入院先后顺序分为对照组与试验组,各53例。对照组接受康复治疗,试验组接受康复治疗联合玻璃酸钠注射液关节腔注射治疗。比较2组治疗前后炎性因子〔白介素6(IL-6)、肿瘤坏死因子α(TNF-α)、C反应蛋白(CRP)〕、膝关节功能评分量表评分、膝关节屈伸肌群肌力,并观察2组不良反应发生情况。结果治疗前,2组IL-6、TNF-α及CRP比较,差异无统计学意义(P>0.05);治疗后,试验组IL-6、TNF-α及CRP低于对照组(P<0.05)。治疗前,2组行走能力、上下楼能力、屈曲下蹲能力及综合能力评分比较,差异无统计学意义(P>0.05);治疗后,试验组行走能力、上下楼能力、屈曲下蹲能力及综合能力评分高于对照组(P<0.05)。治疗前,2组屈肌、伸肌肌力比较,差异无统计学意义(P>0.05);治疗后,试验组屈肌、伸肌肌力高于对照组(P<0.05)。2组不良反应总发生率比较,差异无统计学意义(P>0.05)。结论康复治疗联合玻璃酸钠关节腔注射治疗膝关节损伤的临床效果确切,可减轻患者局部炎性反应,促进膝关节功能恢复,改善肌力。

Objective To study the clinical effect of rehabilitation therapy combined with sodium hyaluronate intraarticular injection in the treatment of knee injury.Methods A total of 106 cases of patients with knee injury were selected from December 2018 to April 2020 in Fuding Hospital,which were divided into control group and experimental group according to the order of admission,53 cases in each group.The control group received rehabilitation therapy,while the experimental group received rehabilitation therapy combined with intraarticular injection of sodium hyaluronate.Inflammatory factors〔interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),C-reactive protein(CRP)〕,knee function score scale scores,knee flexion and extension muscle strength before and after treatment were compared between the two groups,and the incidence of adverse reactions were observed.Results Before treatment,there was no significant difference in IL-6,TNF-αand CRP between the two groups(P>0.05);after treatment,IL-6,TNF-αand CRP in the experimental group were lower than those in the control group(P<0.05).Before treatment,there were significant differences in the scores of walking ability,downstairs ability,flexion ability and comprehensive ability between the two groups(P>0.05);after treatment,the scores of walking ability,downstairs ability,flexion ability and comprehensive ability of the experimental group were higher than those of the control group(P<0.05).Before treatment,there was no significant difference in flexor and extensor abilities between the two groups(P>0.05);after treatment,the flexor and extensor abilities of the experimental group were higher than those of the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Rehabilitation therapy combined with sodium hyaluronate intraarticular injection have an exact clinical effect for knee injury,which can alleviate the local inflammatory reaction of patients,promote the recovery of knee joint function and improve muscle strength.