脑脊液置换治疗小儿蛛网膜下腔出血的临床效果分析

Clinical Effect of Cerebrospinal Fluid Replacement in the Treatment of Subarachnoid Hemorrhage in Children

【目的】探讨脑脊液置换术治疗小儿蛛网膜下腔出血的临床效果。【方法】选取2019年6月至2021年1月本院收治的98例蛛网膜下腔出血患儿,采用随机数表法将其分为观察组和对照组,每组各49例。对照组患儿给予常规的治疗,观察组患儿在常规治疗的基础上采用脑脊液置换治疗。比较两组患儿治疗后意识恢复情况、临床神经功能缺损情况、并发症及日常生活能力评分。【结果】观察组患儿颈项强直恢复时间、意识恢复时间均低于对照组,治疗1周脑脊液恢复正常所占比例高于对照组(P<0.05)。观察组神经缺损患儿所占比例为6.12%(3/49),显著低于对照组的20.41%(10/49),差异有统计学意义(χ^(2)=4.346,P=0.037<0.05)。观察组并发症发生率为8.16%(4/49),低于对照组的22.45%(11/49),差异有统计学意义(χ^(2)=3.857,P=0.049<0.05)。治疗后,两组患者生理机能、生理职能、躯体疼痛、一般健康、精力评分均高于治疗前,且观察组高于对照组,差异均有统计学意义(P<0.05)。【结论】脑脊液置换术治疗小儿蛛网膜下腔出血的临床效果显著,能有效改善患儿神经功能缺损,降低并发症发生率。

【Objective】To investigate the clinical effect of cerebrospinal fluid replacement in the treatment of subarachnoid hemorrhage in children.【Methods】A total of 98 children with subarachnoid hemorrhage treated in our hospital from June 2019 to January 2021 was randomly divided into observation group and control group,with 49 cases in each group.The children in the control group were given routine treatment,and the children in the observation group were treated with cerebrospinal fluid replacement on the basis of routine treatment.The recovery of consciousness,clinical neu-rological deficit,complications and ability of daily living were compared between the two groups.【Results】The recovery time of neck stiffness and consciousness in the observation group were lower than those in the control group.The proportion of cerebrospinal fluid returning to normal after one week of treatment was higher than that in the control group(P<0.05).The proportion of children with nerve defect in the observation group was 6.12%(3/49),which was significantly lower than 20.41%(10/49)in the control group(χ^(2)=4.346,P=0.037<0.05).The incidence of complications in the observation group was 8.16%(4/49),which was lower than 22.45%(11/49)in the control group(χ^(2)=3.857,P=0.049<0.05).After treatment,the scores of physiological function,physiological function,physical pain,general health and energy in the two groups were higher than those before treatment,and the scores in the observation group were higher than those in the control group(P<0.05).【Conclusion】The clinical effect of cerebrospinal fluid replacement in the treatment of subarachnoid hemorrhage in children is significant,which can effectively improve the nerve defect and reduce the incidence of complications.