摘要
目的分析益气通脉汤治疗冠心病心力衰竭(HF)患者心功能和炎性反应的影响。方法选取冠心病HF患者186例,按随机数字表法分为中医组(n=93)与西医组(n=93),西医组予以常规西医治疗,在西医组用药基础上中医组予以益气通脉汤,对比两组疗效和治疗前后心功能[左心室射血分数(LVEF)、舒张末期左心室内径(LVEDD)]、血清炎性因子水平[白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)]。结果中医组总有效率94.62%,较西医组75.57%高(P<0.05);治疗后,中医组LVEF水平较西医组高,LVEDD水平较西医组低(P<0.05);治疗后,中医组血清IL-6、TNF-α水平较西医组低(P<0.05)。结论在西医治疗冠心病HF患者基础上予以益气通脉汤效果显著,可减轻炎症反应,改善心功能。
Objective To analyze the effect of Yiqi Tongmai Decoction on cardiac function and inflammatory response in patients with coronary heart disease and heart failure(HF).Methods 186 patients with HF were selected and randomly divided into traditional Chinese medicine group(n=93)and Western medicine group(n=93).The western medicine group was given conventional western medicine treatment,on the basis of the western medicine group,the Chinese medicine group was given Yiqi Tongmai Decoction.The efficacy and cardiac function(LVEF,LVEDD)and serum inflammatory factor levels(IL-6,TNF-α)before and after treatment were compared between the two groups.The efficacy and cardiac function(LVEF,LVEDD)and serum inflammatory factor levels(IL-6,TNF-α)before and after treatment were compared between the two groups.Results The total effective rate of TCM group was 94.62%(88/93)higher than that of Western medicine group 75.57%(70/93)(P<0.05);after treatment,LVEF level in TCM group was higher than that in western medicine group,LVEDd level was lower(P<0.05);after treatment,serum IL-6 and TNF-αlevels in TCM group were lower than those in western medicine group(P<0.05).Conclusion On the basis of western medicine treatment of HF patients with coronary heart disease,Yiqi Tongmai Decoction has a significant effect,which can reduce inflammation and improve heart function.
作者
李静静
Li Jingjing(TCM Dispensing Room,Gongyi people's Hospital,Gongyi451200,China)
出处
《哈尔滨医药》
2021年第4期126-127,共2页
Harbin Medical Journal
关键词
冠心病
心力衰竭
心功能
白细胞介素-6
肿瘤坏死因子-α
益气通脉汤
Coronary heart disease
Heart failure
Heart function
Interleukin-6
Tumor necrosis factor-α
Yiqi Tongmai Decoction