临床生化检验项目在肝硬化诊断中的效果评价

Evaluation of the effect of clinical biochemical test items in the diagnosis of liver cirrhosis

目的观察临床生化检验项目对肝硬化诊断的应用价值。方法进行生化检验的85例肝硬化患者作为观察组,另外选择同期到本院进行健康体检的85例健康体检者作为对照组。所有研究对象均按常规原则进行常规的生化检验,统计并比较两组研究对象总胆红素(TBIL)、直接胆红素(DBIL)、碱性磷酸酶(ALP)、谷丙转氨酶(ALT)、γ-谷氨酰转肽酶(γ-GT)、天门冬氨酸氨基转移酶(AST)、白蛋白(ALB)、总蛋白(TP)、乙酰胆碱脂酶(ACHE)水平。结果观察组TBIL(78.65±3.24)μmol/L、DBIL(36.75±3.12)μmol/L、ALP(171.54±5.23)U/L、ALT(56.22±6.38)U/L、γ-GT(151.63±2.93)U/L、AST(89.75±8.34)U/L均明显高于对照组的(12.33±0.91)μmol/L、(4.15±0.63)μmol/L、(78.42±2.92)U/L、(17.23±2.36)U/L、(19.64±1.72)U/L、(16.23±1.75)U/L,差异均具有统计学意义(P<0.01)。观察组的ALB(20.73±1.43)g/L、TP(51.62±1.87)g/L、ACHE(2343.63±78.96)U/L均低于对照组的(41.72±2.85)g/L、(73.29±4.46)g/L、(8141.37±135.46)U/L,差异均具有统计学意义(P<0.01)。结论经过临床的生化指标检验可以看出,肝硬化患者的相关生化指标与正常人存在差异。对疑似肝硬化患者积极的进行相关生化检验指标的检查可确定患者的病症,也能为临床的治疗工作提供科学参考。

Objective To observe the practical value of clinical biochemical test items in the diagnosis of liver cirrhosis.Methods 85 patients with liver cirrhosis who had biochemical test were selected as the observation group,and 85 healthy people who had physical examination were selected as the control group.All study subjects underwent routine biochemical tests,and the total bilirubin(TBIL),direct bilirubin(DBIL),alkaline phosphatase(ALP),alanine transaminase(ALT),γ-glutamyl transpeptidase(γ-GT),aspartate aminotransferase(AST),albumin(ALB),total protein(TP),and acetylcholinesterase(ACHE)were counted and compared between the two groups.Results TBIL(78.65±3.24)μmol/L,DBIL(36.75±3.12)μmol/L,ALP(171.54±5.23)U/L,ALT(56.22±6.38)U/L,γ-GT(151.63±2.93)U/L,and AST(89.75±8.34)U/L in the observation group were significantly higher than(12.33±0.91)μmol/L,(4.15±0.63)μmol/L,(78.42±2.92)U/L,(17.23±2.36)U/L,(19.64±1.72)U/L,(16.23±1.75)U/L in the control group,and the differences were statistically significant(P<0.01).ALB(20.73±1.43)g/L,TP(51.62±1.87)g/L,and ACHE(2343.63±78.96)U/L of the observation group were lower than(41.72±2.85)g/L,(73.29±4.46)g/L,(8141.37±135.46)U/L of the control group,and the difference were statistically significant(P<0.01).Conclusion It can be seen that the biochemical indexes of patients with liver cirrhosis are different from those of normal people.Positive detection of related biochemical indexes in patients with suspected liver cirrhosis can determine the patient’s disease,and also provide scientific reference for clinical treatment.