结肠测压技术的发展及其在儿童结肠运动障碍疾病中的应用

The development of colonic manometry and its clinical application in children with colonic dysmotility

结肠运动障碍性疾病是儿童中一种常见的胃肠动力疾病,主要表现为腹胀和便秘。结肠测压可以实时测量结肠腔内压力及结肠肌肉压力波,从而对结肠运动进行定性和定量评估,是目前评估结肠运动最直接的手段。近年来,高分辨率结肠测压技术迅速发展,使临床医师能够更好地了解结肠运动障碍患者结肠收缩活动的病理生理机制。现就其技术发展及其在儿童结肠运动障碍疾病中的研究进展作一综述。

Colonic dysmotility is a common gastrointestinal motility disease in children,with the main manifestations of abdominal distension and constipation.Colonic manometry is currently considered as a standard diagnostic method for assessing colonic motility,which real-time measures intracolonic pressure and the shape and coordination of colonic muscle pressure waves at rest and stimulating states and thus qualitatively and quantitatively assess the colonic movement.Recently,high-resolution colonic manometry has been rapidly developed into a major technique for obtaining more effective information involved in the physiology and/or pathophysiology of colonic contractile activity in colonic dysmotility patients.This review focuses on the development of colonic manometry and its clinical application in children with colonic dysmotility.