摘要
Prion diseases(PrDs)are fatal neurodegenerative conditions that affect humans and other mammals,which consist of sporadic,genetic,and acquired forms in human PrDs[1].The genetic form accounts for approximately 5%–15%of all human PrDs.
基金
National Natural Science Foundation of China[81772197,81401670,81630062]
National Key Research and Development Program of China[2018YFC1200305]
National Science and Technology Major Project of China[2018ZX10102001]
SKLID Development Grant[2019SKLID401,2019SKLID603,2016SKLID603]
the Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences[2018RC330004]。