腹腔镜下卵巢囊肿剥除术治疗卵巢囊肿的效果观察

Observation of the effect of laparoscopic ovarian cystectomy for ovarian cyst

目的分析卵巢囊肿疾病特点,评价腹腔镜下卵巢囊肿剥除术治疗的临床疗效。方法选择106例卵巢囊肿患者,采取随机数字表法分为对照组和观察组,各53例。对照组患者采取开腹术式治疗,观察组患者采取腹腔镜下卵巢囊肿剥除术治疗。比较两组患者手术情况、血清性激素[促黄体生成素(LH)、雌二醇(E_(2))、卵泡刺激素(FSH)]及抗苗勒管激素(AMH)水平。结果观察组患者的手术时间(39.50±5.50)min、术后下床时间(30.20±4.50)h、排气时间(17.20±1.50)h均明显短于对照组的(67.20±6.60)min、(42.80±6.50)h、(21.10±2.30)h,术中出血量(46.50±5.50)ml明显少于对照组的(84.20±6.50)ml,差异均具有统计学意义(P<0.05)。术前,两组患者的LH、E_(2)、FSH、AMH水平比较差异无统计学意义(P>0.05);术后3个月,两组患者的LH、FSH均高于术前,E_(2)水平均低于术前,但观察组的LH、FSH、AMH水平均低于对照组,E_(2)水平高于对照组,差异具有统计学意义(P<0.05);观察组术后3个月AMH水平低于术前,差异具有统计学意义(P<0.05);对照组术前及术后3个月AMH水平比较差异无统计学意义(P>0.05)。结论腹腔镜下卵巢囊肿剥除术治疗卵巢囊肿可以缩短手术时间、减少手术损伤,且有助于患者卵巢储备功能改善,对患者血清性激素水平影响小。

Objective To analyze the characteristics of ovarian cyst and evaluate the clinical efficacy of laparoscopic ovarian cystectomy.Methods A total of 106 patients with ovarian cyst were divided into a control group and an observation group according to random numerical table,with 53 cases in each group.Patients in the control group were treated with laparotomy,and patients in the observation group were treated with laparoscopic ovarian cystectomy.The surgical status,serum sex hormones[luteinizing hormone(LH),estradiol(E_(2)),follicle stimulating hormone(FSH)]and anti-mullerian hormone(AMH)levels were compared between the two groups.Results The operation time(39.50±5.50)min,postoperative off-bed time(30.20±4.50)h,and time to exhaustion(17.20±1.50)h of the observation group were significantly shorter than(67.20±6.60)min,(42.80±6.50)h,and(21.10±2.30)h of the control group;the intraoperative blood loss(46.50±5.50)ml of the observation group was significantly less than(84.20±6.50)ml of the control group;all the differences were statistically significant(P<0.05).Before operation,there was no statistically significant difference in levels of LH,E_(2),FSH and AMH between the two groups(P>0.05).3 months after operation,the LH and FSH of the two groups were higher than those before operation,and E_(2) was lower than those before operation;the LH,FSH and AMH of the observation group were lower than those of the control group,and E_(2) was higher than that of the control group;all the difference was statistically significant(P<0.05).The AMH level in the observation group at 3 months after operation was lower than that before operation,and the difference was statistically significant(P<0.05).In the control group,there was no statistically significant difference in the AMH level before operation and 3 months after operation(P>0.05).Conclusion Laparoscopic ovarian cystectomy for ovarian cysts can shorten the operation time,reduce surgical damage,and help improve the ovarian reserve function of the patients with little effect on the patient’s serum sex hormone level.