降脂管理在冠心病合并2型糖尿病介入治疗中的研究分析

Analysis of blood lipid management in interventional treatment of coronary heart disease with type 2 diabetes mellitus

目的探讨降脂管理在冠心病合并2型糖尿病介入治疗中的临床意义。方法60例冠心病合并2型糖尿病患者,随机分为观察组与对照组,各30例。对照组采用基础治疗与常规降脂方案,观察组在对照组基础上重视综合管理与院后联合降脂干预。比较两组不同时间的总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)水平;出院6个月后不良事件发生情况及满意度。结果出院当天,两组TC、TG水平比较,差异无统计学意义(P>0.05),观察组LDL-C(2.07±0.85)mmol/L低于对照组的(3.14±1.03)mmol/L,差异有统计学意义(P<0.05);出院6个月,观察组TC、TG、LDL-C水平分别为(3.08±0.81)、(1.16±0.56)、(1.88±0.78)mmol/L,均低于对照组的(4.75±1.18)、(3.56±1.16)、(3.14±1.03)mmol/L,差异有统计学意义(P<0.05)。出院6个月后,观察组不良事件发生率3.3%低于对照组的20.0%,护理总满意度96.7%高于对照组的80.0%,差异有统计学意义(P<0.05)。结论重视院中与院后的联合降脂,以及重视细节护理有助于降低冠心病合并2型糖尿病患者不良事件发生率,有效提高患者对临床工作的满意度。

Objective To investigate the clinical significance of blood lipid management in interventional treatment of coronary heart disease with type 2 diabetes mellitus.Methods 60 patients with coronary heart disease and type 2 diabetes mellitus were randomly divided into an observation group and a control group,with 30 patients in each group.The control group received basic treatment and conventional blood lipid management;in addition to these,the observation group focused on comprehensive treatment and blood lipid intervention after discharge.The levels of total cholesterol(TC),triglyceride(TG)and low density lipoprotein cholesterol(LDL-C)at different time were compared between these two groups;and at 6 months after discharge,the incidence of adverse events and patient satisfaction were compared between these two groups.Results On the day of discharge,TC and TG levels were compared between these two groups,the differences were not statistically significant(P>0.05);LDL-C in the observation group was(2.07±0.85)mmol/L,which was lower than(3.14±1.03)mmol/L in the control group,the difference was statistically significant(P<0.05).At 6 months after discharge,the levels of TC,TG and LDL-C in the observation group were(3.08±0.81)mmol/L,(1.16±0.56)mmol/L,(1.88±0.78)mmol/L,which were lower than(4.75±1.18)mmol/L,(3.56±1.16)mmol/L,(3.14±1.03)mmol/L in the control group,the differences were statistically significant(P<0.05).At 6 months after discharge,the incidence of adverse events in the observation group was 3.3%,which was lower than 20.0%in the control group;the nursing satisfaction in the observation group was 96.7%,which was higher than 80.0%in the control group;and the difference was statistically significant(P<0.05).Conclusion Focusing on the combined blood lipid management both in hospital and after discharge and focusing on the nursing details may be helpful to reduce the incidence of adverse events in patients with coronary heart disease with type 2 diabetes mellitus,and effectively improve patient satisfaction with clinical practices.