小柴胡汤加减治疗脑卒中后眩晕患者的临床效果及对血液流变学指标的影响

Clinical effect of addition and subtraction of Xiaochaihu Decoction on patients with vertigo after stroke and its influence on hemorheological indexes

目的分析小柴胡汤加减治疗脑卒中后眩晕患者的临床效果及对血液流变学指标的影响。方法92例脑卒中后眩晕患者,采用随机数字表法分为对照组和观察组,每组46例。对照组患者采取地芬尼多片治疗,观察组患者采用小柴胡汤加减治疗。比较两组患者的治疗效果以及治疗前后血液流变学指标水平、中医证候积分。结果观察组患者治疗总有效率为93.48%,高于对照组的76.09%,差异具有统计学意义(P<0.05)。治疗2周后,观察组患者中医证候积分、全血高切粘度、全血低切粘度、血浆粘度、红细胞比容分别为(8.20±0.80)分、(3.65±0.55)mPa·s、(7.73±1.60)mPa·s、(1.30±0.18)mPa·s、(41.00±6.80)%,均低于对照组的(11.30±1.10)分、(5.65±0.60)mPa·s、(9.85±1.80)mPa·s、(1.88±0.20)mPa·s、(46.50±7.00)%,差异具有统计学意义(P<0.05)。结论采用小柴胡汤加减治疗脑卒中后眩晕能够促进患者血液流变学指标、中医证候积分改善,提升疾病治疗效果。

Objective To analyze the clinical effect of addition and subtraction of Xiaochaihu Decoction on patients with vertigo after stroke and its influence on hemorheological indexes.Methods A total of 92 patients with vertigo after stroke were divided into a control group and an observation group according to random numerical table,with 46 cases in each group.Patients in the control group were treated with difenidol tablets,and patients in the observation group were treated with addition and subtraction of Xiaochaihu Decoction.The therapeutic effects,hemorheology index before and after treatment and traditional Chinese medicine syndrome scores were compared between the two groups.Results The total effective rate of the observation group was 93.48%,which was higher than 76.09%of the control group,and the difference was statistically significant(P<0.05).After 2 weeks of treatment,the traditional Chinese medicine syndrome score,whole blood high shear viscosity,whole blood low shear viscosity,plasma viscosity,and hematocrit of the observation group were(8.20±0.80)points,(3.65±0.55)mPa·s,(7.73±1.60)mPa·s,(1.30±0.18)mPa·s,(41.00±6.80)%,which were all lower than(11.30±1.10)points,(5.65±0.60)mPa·s,(9.85±1.80)mPa·s,(1.88±0.20)mPa·s,(46.50±7.00)%of the control group,and the difference was statistically significant(P<0.05).Conclusion Addition and subtraction of Xiaochaihu Decoction for patients with vertigo after stroke can promote the improvement of hemorheological indexes and traditional Chinese medicine syndrome score,and improve the therapeutic effect of patients.