槐耳颗粒抗结直肠癌作用机制的研究进展

Research Progress in Mechanism of Huaier Granule against Colorectal Cancer

槐耳颗粒作为一类新的抗癌中成药,具有扶正固本、活血消■之功效,主要用于癌症标准化疗基础上的辅助治疗。槐耳颗粒可改善肿瘤患者的生活质量,其在结直肠癌的治疗中具有增强机体免疫力、提高化疗效果、抑制肿瘤转移的作用,对结直肠癌转移患者也具有良好的疗效,这与槐耳颗粒诱导结直肠癌细胞凋亡、抑制结直肠癌细胞侵袭、迁移以及提高化疗敏感性有关。深入研究槐耳颗粒抑制结直肠癌的具体作用机制,可为结直肠癌的治疗提供新思路。

As a new class of anti-cancer Chinese patent medicine,Huaier granules have the effects of strengthening the body,promoting blood circulation and eliminating abdominal symptoms.It is mainly used as adjuvant treatment based on standard cancer chemotherapy,which can improve the quality of life of the patients,with the effects of enhancing immunity,improving chemotherapy efficacy,and inhibiting tumor metastasis.It is also good for patients with metastasis of colorectal cancer.The curative effect of Huaier granule is related to the induction of colorectal cancer cell apoptosis,inhibition of colorectal cancer cell invasion and migration,and improvement of sensitivity to chemotherapy.In-depth study of the specific mechanism of Huaier granules inhibiting colorectal cancer can provide new ideas for the treatment.