肿瘤患者营养状况、疼痛程度及生命质量的相关性研究

Study on the correlation between nutritional status,pain degree and quality of life in tumor patients

目的探讨肿瘤患者营养状况、疼痛程度及与生命质量的关系。方法2017年1月至2020年1月在解放军东部战区总医院就诊的50例肿瘤患者纳入本研究,应用数字分级评分法(NRS)、患者主观整体营养状况量表(PG‐SGA)及生命质量核心问卷(EORTC QLQ‐C30)对患者进行评估,分析疼痛程度、营养状况与生命质量三者之间的关系。结果肿瘤患者疼痛发生率为60%,重度营养不良发生率为46%,其中营养不良患者的疼痛发生率明显高于营养正常的患者(P<0.01);躯体功能、情绪功能、总体健康状况与疼痛程度呈负相关(P<0.05),便秘和气促与疼痛程度呈正相关(P<0.05);营养状况得分与生活质量评分中躯体功能、角色功能、情绪功能、总体健康状况呈负相关(P<0.05),与疲劳、疼痛、食欲丧失呈正相关(P<0.01)。结论肿瘤患者疼痛发生率和营养不良发生率高,严重影响患者的生命质量,在临床治疗工作中需加以重视。

Objective To explore the relationship between nutritional status,pain degree and life quality of tumor patients.Methods A total of 50 cancer patients in General Hospital of Eastern Theater Command were investigated by demographic information questionnaire,numerical rating scale(NRS)、patient generated subjective global assessment(PG⁃SGA)and EORTC QLQ⁃C30.Results The incidence of pain in cancer patients was 60%and the incidence of severe malnutrition was 46%.Comparison of the number of pain cases with different nutritional status was statistically significant(P<0.01).Somatic function,emotional function,overall health status were negatively correlated with pain(P<0.05)while constipation and shortness of breath were positively correlated with pain(P<0.05).Nutritional status scores were negatively correlated with somatic function,role function,emotional function,overall health status in the quality of life score(P<0.05),and positively correlated with fatigue,pain,loss of appetite(P<0.01).Conclusion The incidence of pain and malnutrition in cancer patients is high and affects each other,so it is worth further exploring its correlation.