内镜窄带成像技术在早期喉癌及癌前病变鉴别诊断中的价值

Clinical Value of Endoscopic Narrow-Band Imaging in the Diagnosis of Early Laryngeal Cancer and Precancerous Lesions

目的:探讨内镜窄带成像技术在早期喉癌及癌前病变鉴别诊断中的临床价值。方法:选取2019年1月至2020年12月在梅州市人民医院耳鼻咽喉科就诊、经电子鼻咽喉镜筛查发现喉部肿物怀疑恶性病变的96例患者为研究对象,分别应用普通白光电子喉镜、内镜窄带成像技术及病理活检进行检查,记录两种检测模式的良性、可疑恶性、恶性病变病例数;并以病理活检结果作为金标准,比较两种检测模式的诊断效能。结果:96例患者的病理活检结果显示,恶性病变率为30.21%(29/96),非恶性病变率为69.79%(67/96);白光模式组的恶性病变诊断率为22.92%(22/96),非恶性病变诊断率为77.08%(74/96);内镜窄带成像模式组的恶性病变诊断率为28.13%(27/96),非恶性病变诊断率为71.87%(69/96)。内镜窄带成像模式组的诊断灵敏度、特异度、准确度均比白光模式组高,差异具有统计学意义(P<0.05)。结论:内镜窄带成像技术在早期喉癌及癌前病变鉴别诊断中的诊断效能较高,有利于及早发现病变,为后续治疗提供指导。

Objective To investigate the clinical value of endoscopic narrow-band imaging in the diagnosis of early laryngeal cancer and precancerous lesions.Methods From January 2019 to December 2020,96 patients with suspected malignant lesions of the throat detected by electronic nasopharyngolaryngoscope in the department of ENT of Meizhou People’s Hospital were selected as object of study.All patients were performed white light endoscopy and endoscopic narrow-band imaging and pathological biopsy.The number of benign lesions,suspicious lesions and malignant lesions of the two test modes were recorded.The pathological results was used as gold standard to evaluate the diagnostic efficacy of the two test modes.Results The Pathological biopsies results of 96 patients showed that the rate of malignant lesion of patients was 30.21%(29/96),and the rate of non-malignant lesion was 69.79%(67/96).The diagnosis rate of malignant lesion of white light mode group was 22.92%(22/96),and the diagnosis rate of non-malignant lesion of white light mode group was 77.08%(74/96).The diagnosis rate of malignant lesion of endoscopic narrow-band imaging mode group was 28.13%(27/96),and the diagnosis rate of non-malignant lesion of endoscopic narrow-band imaging mode group was 71.87%(69/96).The diagnostic sensitivity,specificity and accuracy in the endoscopic narrow-band imaging mode group were higher than those in the white light mode group,and the differences were statistically significant(P<0.05).Conclusions Endoscopic narrow-band imaging has a high diagnosis efficiency in the diagnosis of early laryngeal cancer and precancerous lesions,which is conducive to the early detection of lesions and provides guidance for subsequent treatment.