头孢哌酮钠舒巴坦钠的临床价值与不良反应分析

Analysis of the Clinical Value and Adverse Reactions of Cefoperazone Sodium and Sulbactam Sodium

目的:探究头孢哌酮钠舒巴坦钠临床应用对细菌感染性疾病的治疗效果及不良反应情况。方法:选取2018年1月至2020年1月四会市人民医院收治的100例细菌性感染疾病患者,以简单随机化法分为对照组和观察组,各50例。对照组头孢噻肟钠治疗,观察组头孢哌酮钠舒巴坦钠治疗,分析两组细菌性感染疾病患者治疗结果的差异性。结果:观察组患者的治疗总有效率、细菌清除率明显高于对照组,差异具有统计学意义(P<0.05);观察组治疗后的C反应蛋白(CRP)、白细胞计数(WBC)水平低于对照组,其血小板计数(PLT)水平高于对照组,差异具有统计学意义(P<0.05);观察组不良反应发生率为8.00%,明显低于对照组的24.00%,差异具有统计学意义(P<0.05)。结论:细菌性感染疾病患者接受头孢哌酮钠舒巴坦钠治疗,可较好地将细菌清除,且不良反应发生率低,安全有效。

Objective To explore the interference value and adverse reactions of cefoperazone sodium and sulbactam sodium in the clinical application of Western medicine.Methods 100 patients with bacterial infectious diseases treated in Sihui people’s Hospital from January 2018 to January 2020 were divided into simple randomization method,with 50 cases in the control group and 50 cases in the observation group.The control group was treated with cefotaxime sodium and the observation group was treated with cefoperazone sodium and sulbactam sodium.The differences of treatment results between the two groups were analyzed.Results The total effective rate and bacterial clearance rate of the observation group were significantly higher than those of the control group(P<0.05);The levels of C-reactive protein(CRP)and leukocyte count(WBC)in the observation group were lower than those in the control group,and the level of platelet count(PLT)in the observation group was higher than those in the control group(P<0.05);The incidence of adverse reactions in the observation group was 8.00%,which was lower than 24.00%in the control group P<0.05).Conclusion Cefoperazone sodium and sulbactam sodium can effectively eliminate bacteria in patients with bacterial infectious diseases,and the incidence of adverse reactions is low,safe and effective.