饮用油茶与糖尿病患病风险的关联性分析

Association analysis of oil tea consumption with diabetes mellitus risk

目的探讨饮用油茶与糖尿病患病风险的关联。方法选取广西社区人群13422例为研究对象,其中2046例来自饮用油茶地区的广西桂林市和恭城县社区人群,11376例来自不饮用油茶地区的广西南宁市、玉林市健康体检人群。采用结构化问卷,调查研究对象的饮用油茶史、吸烟、饮酒、运动、近12个月饮食频率等信息。测量并收集血压、体质量指数(BMI)、血糖、血脂结果,统计饮用油茶人群中糖尿病、糖尿病前期患病情况。通过匹配的病例对照研究,按照性别年龄匹配纳入病例和对照进行分析。使用条件logistic回归模型评估饮用油茶与糖尿病及糖尿病前期患病风险之间的关系。结果总体13422例研究对象中,饮用油茶者3980例、不饮用油茶者9442例。饮用油茶人群中,检出糖尿病患者796例纳入糖尿病组,按1:4匹配对照者3184例纳入糖尿病-对照组;检出糖尿病前期患者870例纳入糖尿病前期组,按1:4匹配对照者3480例纳入糖尿病前期-对照组。在糖尿病和糖尿病前期组中,对协变量进行校正后,饮用油茶均与糖尿病(OR=0.47,95%CI为0.26~0.82,P=0.008)和糖尿病前期(OR=0.41,95%CI为0.23~0.73,P=0.003)的风险降低显著相关,尤其在超重或肥胖者中存在显著相关(糖尿病:OR=0.37,95%CI为0.15~0.99,P=0.048;糖尿病前期:OR=0.33,95%CI为0.13~0.86,P=0.023)。结论饮用油茶显著降低糖尿病和糖尿病前期的患病风险。饮用油茶可能是预防和控制糖尿病的有益措施。

Objective To investigate the associations of oil tea consumption with the risk of diabetes mellitus(DM).Methods A total of 13,422 adults from Guangxi Community were recruited,in which 2,046 people were from Guangxi Guilin city and Gongcheng county community with oil tea drinking and 11,376 people were from Guangxi Nanning and Yulin,and without oil tea drinking.A structured questionnaire was used to investigate the subjects’consumption history of oil tea,smoking,drinking,exercise,and diet frequency in recent 12 months.Blood pressure,body mass index(BMI),blood glucose and blood lipid were measured and collected,and the statistics of diabetes and pre-diabetes prevalence in people drinking oil tea was conducted.The cases and controls were selected by sex and age matching.Conditional logistic regression model was used to assess the association of oil tea consumption with the risk of diabetes and prediabetes.Results Among 13,422 subjects,3,980 people were oil-tea drinkers and 9,442 people were non-oil-tea drinkers.Among the oil-tea drinkers,796 diabetic patients were included in the diabetes group,and 3,184 subjects were included in the diabetes-control group according to 1:4 matched control group and 870 prediabetes patients were included in the prediabetes group,and3,480 subjects were included in the prediabetes-control group according to 1:4 matched control group.After adjustment for covariates,oil tea consumption was significantly associated with decreased risk of DM(OR=0.47,95%CI was 0.26-0.82,P=0.008)and prediabetes(OR=0.41,95%CI was 0.23-0.73,P=0.003),particularly in the overweight/obesity subjects(DM:OR=0.37,95%CI was 0.15-0.99,P=0.048;prediabetes:OR=0.33,95%CI was 0.13-0.86,P=0.023).Conclusions Drinking oil tea singnificantly reduced the risk of diabetes and prediabetes.These findings suggest oil tea could be potentially used to prevent and control diabetes.